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Mercury Ions — A Tool to Study the Specific Role of Individual Subunits in the Allosteric Interaction of Arthropod Hemocyanins

  • Jürgen Markl
  • Anette Savel
  • Birgit Knabe
  • Heide Storz
  • Thomas Krabbe
  • Stephan Abel
  • Barbara Markl

Abstract

Native 37S hemocyanin of the tarantula Eurypelma californicum shows a complex oxygen binding behavior with low oxygen affinity, strong normal Bohr effect, and high cooperativity (Hill coefficient beyond 7). All three effects are created by an interaction of the 24 constituent subunits, because isolated subunits have neither Bohr effect nor cooperativity, and their oxygen affinity is high (1). The oxygen binding behavior of the native 24-mer establishes itself by an interaction of two dodecamers which, on their part, consist of two interacting hexamers (2).

Keywords

Oxygen Affinity Oxygen Binding Individual Subunit Bohr Effect Subunit Type 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • Jürgen Markl
    • 1
  • Anette Savel
    • 1
  • Birgit Knabe
    • 1
  • Heide Storz
    • 1
  • Thomas Krabbe
    • 1
  • Stephan Abel
    • 1
  • Barbara Markl
    • 1
  1. 1.Zoologisches InstitutUniversität MünchenMünchen 2Germany

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