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Neuroendocrine Projections to the Median Eminence

  • Conference paper
Morphology of Hypothalamus and Its Connections

Part of the book series: Current Topics in Neuroendocrinology ((CT NEUROENDOCRI,volume 7))

Abstract

Advertisements in the Sunday newspaper boast of how to command your pituitary gland with a simple tablet, but in fact, regulation of anterior pituitary function is the result of complex interactions of cells in the pituitary with hormones from the gland itself, from peripheral target tissues, and from neurons in the central nervous system. Within the brain, neuronal signals are integrated with blood-borne hormonal messages. These are directed to a set of neuroendocrine neurons whose axons extend to the floor of the third ventricle, the median eminence, where they terminate within the perivascular spaces of the primary capillary plexus of the pituitary portal system. The neurohormones are then carried via the portal system to the anterior pituitary where they effect or inhibit release of the pituitary hormones.

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Authors and Affiliations

  1. Department of Neurobiology and Anatomy, University of Rochester, School of Medicine and Dentistry, Rochester, NY, 14642, USA

    G. E. Hoffman, C. J. Phelps & J. R. Sladek Jr.

  2. Mental Health Research Institute, University of Michigan, Ann Arbor, MI, 48109, USA

    H. Khachaturian

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  1. G. E. Hoffman
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  2. C. J. Phelps
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  3. H. Khachaturian
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  4. J. R. Sladek Jr.
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Editors and Affiliations

  1. Pharmakologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 366, 6900, Heidelberg, Germany

    Detlev Ganten M.D., Ph.D.

  2. Rockefeller University, York Avenue, and 66th Street, New York, NY, 10021, USA

    Donald Pfaff Ph.D.

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Hoffman, G.E., Phelps, C.J., Khachaturian, H., Sladek, J.R. (1986). Neuroendocrine Projections to the Median Eminence. In: Ganten, D., Pfaff, D. (eds) Morphology of Hypothalamus and Its Connections. Current Topics in Neuroendocrinology, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71461-0_5

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