Conditions for Neuronal Survival and Growth as Assessed by the Intracerebral Transplantation Technique in Lesion Models of the Adult CNS

  • Ole Isacson
  • Anders Björklund
  • Stephen B. Dunnett
Part of the NATO ASI Series book series (volume 2)


The development of intracerebral grafting techniques has provided neurobiology with a new tool for analysis of structural and functional plasticity in the central nervous system (CNS). Neural grafting provides an in vivo test-system which is a complementary to in vitro cell-culture techniques for the study of cellular and trophic interactions in the CNS (1–14).


Nerve Growth Factor Sciatic Nerve Adult Central Nervous System Ibotenic Acid Trans Plant 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • Ole Isacson
    • 1
  • Anders Björklund
    • 1
  • Stephen B. Dunnett
    • 2
  1. 1.Dept. of HistologyUniversity of LundLundSweden
  2. 2.Dept. of Experimental PsychologyUniversity of CambridgeCambridgeEngland

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