Neuropathology pp 105-150 | Cite as

Dementia in Middle and Late Life

  • C. L. Scholtz
Part of the Current Topics in Pathology book series (CT PATHOLOGY, volume 76)


A major problem in the study of dementia has been the production of a definition. That most commonly used is that of Lishman (1978): — an acquired global impairment of intellect, memory and personality, but without impairment of consciousness. This definition is important because it identifies the clinical nature of the problem and directs study to those areas of the brain which have a major part to play in these functions. It also excludes patients with clouding of consciousness (delerium) as a major symptom, or when the confused state is secondary to toxic and infective intracranial or extracranial disease.


Neurofibrillary Tangle Cerebral Amyloid Angiopathy Late Life Senile Dementia Neuritic Plaque 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1988

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  • C. L. Scholtz

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