Factors Influencing Motor Nerve Growth

  • C. E. Henderson
Conference paper


By far the best-characterized factor affecting nerve growth is the nerve growth factor (NGF), identified in 1956 by Cohen and Levi-Montalcini (for review, see Thoenen and Barde 1980), and subsequently sequenced and cloned. The purified protein has three major effects on sympathetic and sensory neurons cultured at appropriate development stages: it is required for cell survival, and enhances neurite outgrowth and neurotransmitter synthesis.


Nerve Growth Factor Neurite Outgrowth Sympathetic Innervation Spinal Neuron Spinal Cord Cell 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • C. E. Henderson
    • 1
  1. 1.Neurobiologie MoléculaireInstitut PasteurParisFrance

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