Microphysiological Studies on Oxygenation of Normal or Ischaemic Myocardium
This paper contains some observations on the state of oxygenation of myocardial tissue that were obtained during studies on the collateral supply of oxygen during haemodilution and during the production of myocardial infarction , It was possible to obtain on-line partial pressures of oxygen (PO2) from the myocardium for extended periods, and very high fidelity recordings were produced. It was thus possible to make accurate observations of myocardial oxygenation in relation to flow in the main coronary arteries and in relation to areas of ischaemic hypoxia.
KeywordsCatheter Ischemia Lactate Cage Bromide
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- 3.Erdmann W (1980) Continuous on-line acquisition of tissue PO2, tissue perfusion, oxygen diffusion parameters and neuronal activity. In: Kimmich HP (ed) Monitoring of vital parameters during extra-corporeal circulation. Karger, Basel, p 73Google Scholar
- 4.Faithfull NS, Fennema M, Essed CE, Erdmann W, Jeekel H, Lapin R (1983) Collateral oxygenation of the ischemic myocardium - the effect of viscosity and oxygen carrying fluorocarbons. In: Bolin RB, Geyer RP, Nemo GJ (eds) Advances in blood substitute research. Liss, New York, p 229Google Scholar
- 5.Gregg DE (1963) Physiology of the coronary circulation. The George E Brown memorial lecture. Circulation 27:1128Google Scholar
- 6.Harris SA (1941) The spread of excitation in turtle, dog, cat and monkey ventricles. Am J Physiol 134:319Google Scholar
- 7.Marston EL, Barefoot CA, Spencer MP (1959) Non-cannulating measurements of coronary blood flow. Surg Forum 10:336Google Scholar
- 8.Reves JG, Erdmann W, Mardis M, Karp RB, King M, Lell WA (1978) Evidence for existence of myocardial steal. In: Silver IA et al. (eds) Oxygen transport to tissue, III. Plenum, New York, p 755Google Scholar
- 10.Tillmans H, Ikeda S, Hansen H, Sarma JSM, Fauvel JM, Bing RJ (1974) Microcirculation in the ventricle of the dog and turtle. Circ Res 34:561Google Scholar