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Therapeutic Effect of Selective 5HT Reuptake Inhibitors in Comparison with Tricyclic Antidepressants

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Clinical Pharmacology in Psychiatry

Part of the book series: Psychopharmacology Series ((PSYCHOPHARM,volume 3))

Abstract

A recent count suggests that there are more than a hundred compounds at various stages of development as possible new antidepressants. These include “pure” norepinephrine and serotonin reuptake inhibitors. Most of these compounds, however, have not reached the stage of clinical research at which it would be wise, from a clinical point of view, to discuss their efficacy or draw conclusions on toxicity and unwanted side effects. This is especially evident for the pure norepinephrine reuptake blockers.

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Author information

Authors and Affiliations

  1. Department of Psychiatry, Odense University Hospital, DK-5000, Odense C, Denmark

    P. Kragh-Sørensen

  2. Department of Clinical Pharmacology, Odense University Hospital, DK-5000, Odense C, Denmark

    L. F. Gram

  3. Research Division, Danish Ferrosan Group, DK-2860, Søborg, Denmark

    P. le Fèvre Honoré

Authors
  1. P. Kragh-Sørensen
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  2. P. le Fèvre Honoré
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  3. L. F. Gram
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Institute of Medical Biology, University of Tromsø School of Medicine, N-9001, Tromsø, Norway

    Svein G. Dahl Cand Real, Dr. Philos. (Professor of Pharmacology) (Professor of Pharmacology)

  2. Department of Clinical Pharmacology, School of Medicine, Odense University, DK-5000, Odense C, Denmark

    Lars F. Gram MD (Professor of Clinical Pharmacology) (Professor of Clinical Pharmacology)

  3. Clinical Neuroscience Branch, National Institute of Mental Health, Building 10, Room 4N214, 20205, Bethesda, MD, USA

    Steven M. Paul MD (Chief) (Chief)

  4. Section on Clinical Psychopharmacology, Laboratory of Clinical Science, Building 10, National Institute of Mental Health, 20205, Bethesda, MD, USA

    William Z. Potter MD, PhD (Chief) (Chief)

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© 1987 Springer-Verlag Berlin Heidelberg

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Kragh-Sørensen, P., le Fèvre Honoré, P., Gram, L.F. (1987). Therapeutic Effect of Selective 5HT Reuptake Inhibitors in Comparison with Tricyclic Antidepressants. In: Dahl, S.G., Gram, L.F., Paul, S.M., Potter, W.Z. (eds) Clinical Pharmacology in Psychiatry. Psychopharmacology Series, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71288-3_17

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  • DOI: https://doi.org/10.1007/978-3-642-71288-3_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71290-6

  • Online ISBN: 978-3-642-71288-3

  • eBook Packages: Springer Book Archive

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