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Das schmerzhafte Experiment an Tier und Mensch

  • W. Tolksdorf
Conference paper
Part of the Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine book series (A+I, volume 193)

Zusammenfassung

Schmerz ist ein unangenehmes Sinnes- und Gefühlserlebnis, das mit aktueller oder potentieller Gewebsschädigung verknüpft ist oder mit Begriffen einer solchen Schädigung beschrieben wird. Bereits diese Definition macht deutlich, wie komplex das Phänomen Schmerz ist und welche Schwierigkeiten den Experimentator erwarten.

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Literatur

  1. 1.
    Akil H (1972) Monoaminergic mechanisms underlying stimulationproduced analgesia. Doctoral Dissertation, U.C.L.A. In: Bonica JJ, (ed) Advances in Neurology, Vol. 4 International Symposium on Pain. Raven, New York, 1974, p 261Google Scholar
  2. 2.
    Bangert J, Tolksdorf W (1984) Schmerzdiagnostik und Schmerzmessung - Teil 1 u. 2. Anästh Intensivther Notfallmed 19: 221PubMedCrossRefGoogle Scholar
  3. 3.
    Beecher HK (1956) Evidence for increased effectiveness of placebos with increased stress. Am J Physiol 187: 163PubMedGoogle Scholar
  4. 4.
    Bond MR: Pain. Its nature, analysis and treatment. EdinburghGoogle Scholar
  5. 5.
    Carroll MN, Lim RKS (1960) Observations on the neuropharmacology of morphine and morphinlike analgesia. Archives internationales des pharmacodynamic et de thérapie 125: 383Google Scholar
  6. 6.
    Charpentier J: Analysis and measurement of pain in animals. A new conception of pain. In: Soulairac A, Cahn J, Charpentier J (eds) Pain. Academic Press, London, p d171Google Scholar
  7. 7.
    Colombo MR: De re anatomica Libri XV (Repr. 1983). Culture et Civilisation, Bruxelles, p 224Google Scholar
  8. 8.
    Galen: On anatomical procedures. Translated by Duckwoth WLH, Lyons MC, Towers B (1962). University Press, Cambridge, p 85Google Scholar
  9. 9.
    Hendershof LC, Forsaith J (1959) Antagonism of the frequency of Phenylquinone-induced writhing in the mouse by weak analgesics and non-analgesics. J of Pharmacol and Experimental Ther 125: 237Google Scholar
  10. 10.
    Kremer E, Atkinson JH, Ignelzi RJ (1981) Measurement of pain: patient preference does not confound pain measurement. Pain 10: 241PubMedCrossRefGoogle Scholar
  11. 11.
    Lim KS, Guzman F (1968) Manifestations of pain in analgesic evaluation in animals and man. In: Soulairac A, Cahn J, Charpentier J (eds) Pain. Academic Press, London, p 119Google Scholar
  12. 12.
    Melzack R (1985) President’s message. Newsletter. Internat Association for the study of painGoogle Scholar
  13. 13.
    Ohnhaus EE, Adler R (1975) Methodological problems in the measurement of pain: A comparison between the verbal rating scale and the visual analogue scale. Pain 1: 379PubMedCrossRefGoogle Scholar
  14. 14.
    Poggio GF, Mountcastle VB (1960) A study of the functional contributions of the lemniscal and spinothalamic system of somatic sensibility. Central nervous mechanisms in pain. Bulletin of Johns Hopkins Hospital 106: 266Google Scholar
  15. 15.
    Schmidt RF, Struppler A (1982) Der Schmerz. Ursachen, Diagnose, Therapie. Piper, MünchenGoogle Scholar
  16. 16.
    Scott J, Huskisson EC (1976) Graphic representation of pain. Pain 2: 175PubMedCrossRefGoogle Scholar
  17. 17.
    Sternbach RA (1976) The need for an animal model of chronic pain. Pain 1: 2Google Scholar
  18. 18.
    Sternbach RA: Clinical aspects of pain. In: Sternbach RA (ed) The psychology of pain. New YorkGoogle Scholar
  19. 19.
    Sternbach RA (1983) Ethical considerations in pain research. In: Melzack R (ed) Pain Measurement and Assessment. Raven Press, New YorkGoogle Scholar
  20. 20.
    Tröhler U (1985) Was ist neu? - Der medizinische Tierversuch im Meinungsstreit. Swiss Pharma 7, Nr. 5, 7Google Scholar
  21. 21.
    Vyklicky L (1984) Methods of testing pain mechanisms in animals. In: Wall PD, Melzack R (eds) Textbook of pain. Churchill Livingstone, EdinburghGoogle Scholar
  22. 22.
    Wolff BB (1984) Methods of testing pain mechanisms in normal man. In: Wall PD, Melzack R (eds) Textbook of pain. Churchill Livingstone, EdinburghGoogle Scholar
  23. 23.
    Zimmermann M (1976) Neurophysiology of nociception. International Review of Physiology. Neurophysiology II, 10: 221Google Scholar
  24. 24.
    Zimmermann M (1984) Ethical considerations in relation to pain in animal experimentation. In: Bankowski Z, Howard-Jones H (eds) Biomedical Research involving animals. GenevaGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

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  • W. Tolksdorf

There are no affiliations available

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