Imaging of Endocrine-Active Malignant Tumors

  • J. L. Doppman
Conference paper

Abstract

The diagnosis of malignant endocrine-active tumors is a biochemical, not a radiological responsibility. As in the case of benign endocrine tumors, the role of the radiologist is largely one of localization. The distinction between benign and malignant endocrine-active tumors cannot be based on radiological findings unless there is evidence of metastatic disease. Aside from size, arteriographic, ultrasonic, and CT findings cannot reliably distinguish between benign and malignant endocrine tumors. This is not surprising, since the histologic diagnosis often must be based on the presence of metastases and not on histologic criteria of malignancy.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Hussain S, Belldegrun A, Seltzer SE, Richie JB, Gittes RF, Abrams HL (1985) Differentiation of malignant from benign adrenal masses; predictive indices on computed tomography. AJR 144: 61–65PubMedGoogle Scholar
  2. 2.
    Glazer HS, Weyman PJ, Sagel SS, Levitt RG, McClennan BL (1982) Nonfunctioning adrenal masses; incidental discovery on computed tomography. AJR 139: 81–85PubMedGoogle Scholar
  3. 3.
    Copeland PM (1983) Incidentally discovered adrenal mass. An Intern Med 98: 940–945Google Scholar
  4. 4.
    Oliver TW, Bernadino ME, Miller JI, Mansour K, Greene D, Davis WA (1984) Isolated adrenal masses in nonsmall cell bronchogenic carcinoma. Radiology 153: 217–218PubMedGoogle Scholar
  5. 5.
    Reinig JW, Doppman JL, Dwyer AJ, Johnson AR, Knop RH (1985) Distinction between adrenal adenomas and metastases using MR imaging. J Comput Assist Tomogr 9 (5): 898–901PubMedCrossRefGoogle Scholar
  6. 6.
    Reinig JW, Doppman JL, Dwyer AJ, Johnson AR, Knop RH (1985) Adrenal masses differentiated by MR. Radiology 158: 81–84Google Scholar
  7. 7.
    Reinig JW, Doppman JL, Dwyer AJ, Frank JA (1986) MRI of the indeterminate adrenal mass. AJR (in press)Google Scholar
  8. 8.
    Fink IJ, Reinig JW, Dwyer AJ, Doppman JL, Linehan WM, Keiser HR (1985) MR imaging of pheochromocytomas. J Comput Assist Tomogr 9 (3): 454–458PubMedCrossRefGoogle Scholar
  9. 9.
    Findling JW, Tyrrell JB (1986) Occult ectopic secretion of corticotropin. Arch Int Med 146: 929–933CrossRefGoogle Scholar
  10. 10.
    Oldfleld EH, Chrousos GP, Schulte HL, Schaaf M, McKeever PE, Krudy AG, Cutter GB Jr, Loriaux DL, Doppman JL (1985) Preoperative lateralization of ACTH-secreting pituitary microadenomas by bilateral and simultaneous inferior petrosal venous sinus sampling. N Engl J Med 312 (2): 100–103CrossRefGoogle Scholar
  11. 11.
    Fulkerson WJ, Newman JH (1984) Endogenous Cushing’s syndrome complicated by Pneumocystis carinii pneumonia. Am Rev Respir Di 129: 188–189Google Scholar
  12. 12.
    Krudy AG, Doppman JL, Marx SJ, Brennan MF, Spiegel A, Aurbach GD (1982) Radiographic findings in recurrent parathyroid carcinoma. Radiology 142: 625–629PubMedGoogle Scholar
  13. 13.
    Danforth DN Jr, Görden P, Brennan MF (1984) Metastatic insulin-secreting carcinoma of the pancreas; clinical course and the role of surgery. Surgery 96: 1027–1036PubMedGoogle Scholar
  14. 14.
    Jensen RT, Gardner JD, Raufman JP, Pandol SJ, Doppman JL, Collen MJ (1983) Zollinger- Ellison syndrome: current concepts and management. Ann Intern Med 98: 59–75PubMedGoogle Scholar
  15. 15.
    Norton JA, Sugarbaker PH, Doppman JL, Wesley RA, Maton PN, Gardner JD, Jensen RT (1986) Aggressive resection of metastatic disease in selected patients with malignant gastrinomas. Ann Surg 203 (4): 352–359PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • J. L. Doppman

There are no affiliations available

Personalised recommendations