Zusammenfassung
Das Syndrom der EPH-Gestose beinhaltet in außergewöhnlicher Weise eine Reihe von Veränderungen, die sowohl die Mutter als auch die utero-feto-plazentare Einheit, und damit das Kind, betreffen. Die schwere Form der EPH-Gestose und der Eklampsie ist immer noch eine der häufigsten mütterlicher Todesfälle und steht nach der Frühgeburtlichkeit an 2. Stelle der perinatalen Morbidität und Mortalität.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Atlas M, Barkai G, Menczer J, Houlou N, Liebermann P (1982) Thrombotic thrombocytopenic purpura in pregnancy. Br J Obstet Gynaecol 89:476–479
Aznar J, Gilabert J, Estelles A, Fernandez MA, Villa P, Aznar JA (1982) Evaluation of the soluble fibrin monomer complexes and other coagulation parameters in obstetric patients. Thromb Res 27: 691–701
Blombäck B, Hessel B, Hogg D, Therkildsen L (1978) A two-step fibrinogen-fibrin transition in blood coagulation. Nature 275:501–504
Bodzenta A, Thromson JM, Poller L (1980) Prostacyclin activity in amniotic fluid in pre-eclampsia. Lancet 11:650
Bonnar J, McNicol GP, Douglas AS (1971) Coagulation and fibrinolytic systems in pre-eclampsia and eclampsia. Br Med J 11:12–16
Bussolino F, Benedetto C, Massobrio M, Canussi G (1980) Maternal vascular prostacyclin activity in preeclampsia. Lancet 11:702
Chen YC, McLeod B, Hall ER, Wu KK (1981) Accelerated prostacyclin degradation in thrombotic thrombocytopenic purpura. Lancet 11:267–269
Dadak C (1983) Anwendung von Prostazyklin und Thromboxan in Geburtshilfe und Gynäkologie. MMW 125:655–658
Dadak C, Kefalides A, Sinzinger H (1983) Hemostatic regulation via prostaglandins in gestosis. In: Janisch H, Reinold E (eds) Dilemmas in gestosis. Int. Symposium Vienna. Thieme, Thieme-Stratton, Stuttgart New York, pp 60–62
Diekmann WJ (1936) Blood and plasma volume changes in eclampsia. Am J Obstet Gynecol 32: 927–936
Dintenfass L (1982) On changes in aggregation of red cells, blood viscosity and plasma viscosity during normal gestation. Clin Hemorheol 2:175–188
Ebert CH, Beller FK (1979) High molecular weight fibrin derivatives in pre-eclampsia. In: Serneri GGN, Prentice CRM (eds) Haemostasis and thrombosis. Proceedings of the Serono Symposia, vol 15. Academic, London New York, pp 625–630
Edgar W, Millop C, Howie PW (1977) Composition of soluble fibrin complexes in pre-eclampsia. Thromb Res 10:567–574
Gollwitzer R, Hafter R, Timpl R, Graeff H (1977) Immunological assay for a carboxyterminal peptide of the fibrinogen Aa-chain in normal and pathological sera. Thromb Res 11:859–868
Graeff H, Hafter R (1982) Detection and relevance of crosslinked fibrin derivatives in blood. Semin Thromb Hemost 8:57–68
Graeff H, Kuhn W (1980) Coagulation disorders in obstetrics. Thieme Stuttgart New York, Saunders, Philadelphia London Toronto
Graeff H, Hafter R, Bachmann L (1979) Subunit and macromolecular structure of circulating fibrin from obstetric patients with intravascular coagulation. Thromb Res 16:313–328
Hafter R, Graeff H (1976) Estimation of soluble fibrin monomer complexes by agarose gel filtration. In: Davidson JF, Samama MM, Desnoyers PC (eds) Raven, New York, pp 137–149
Heilmann L, Ludwig H (1980) Die gestörte Mikrozirkulation bei der Gestose. Z Geburtshilfe Perinatol 184:187–194
Heilmann L, Siekmann U (1981) Die gestörte Mikrozirkulation bei der Gestose und der maternofetale Sauerstoffaustausch. Arch Gynakol 232:77–78
Howie PW, Prentice CRW, Forbes CD (1975) Failure of heparin therapy to affect the clinical course of severe pre-eclampsia. J Obstet Gynaecol Br Commonw 82:711–717
Kaibara M, Marumoto Y, Taniguchi I, Kobayashi T (1982) Blood viscosity at a low shear rate in normal and abnormal pregnancies. Clin Hemorheol 2:209–217
Lewis PJ, Boylan P, Friedman LA, Hensby CN, Downing I (1980) Prostacyclin in pregnancy. Br Med J 280:1581–1582
McMay DG (1965) Disseminated intravascular coagulation. An intermediary mechanism of disease. Harper & Row, New York
McMillop C, Howie PW, Forbes CD (1976) Soluble fibrinogen/fibrin complexes in pre-eclampsia. Lancet 1:56–58
Mendling W (1983) Präeklampsie mit hämolytischer Anämie, Thrombocytopenie, Leber- und Nierenbeteiligung - eine ungewöhnliche Form der schweren Gestose. Geburtshilfe Frauenheilkd 43: 332–335
Ozanne P, Miller FC, Meiselman HJ (1983) RBC aggregation in diabetic and pre-eclamptic pregnancy. Clin Hemorheol 1:145–154
Perkins RP (1979) Thrombocytopenia in obstetric syndromes. A review. Obstet Gynecol Surv 34: 101–114
Pritchard JA, Weisman R Jr, Ratnoff OD, Visbourgh G (1954) Intravascular hemolysis. Thrombocytopenia and other hematologic abnormities associated with severe toxemia of pregnancy. N Engl J Med 250:89–98
Pritchard JA, Cunningham FG, Mason RA (1976) Coagulation changes in eclampsia: Their frequency and pathogenesis. Am J Obstet Gynecol 124:855–859
Redman CWG, Denson KWE, Beilin LJ (1977) Factor VIII consumption in pre-eclampsia. Lancet II: 1249–1252
Remuzzi G, Rossi EC, Misiani R, Marchesi D, Mecca G, de Gaetano G, Donati MB (1980) Prostacyclin and thrombotic microangiopathy. Semin Thromb Hemostas 6:391–394
Sagen N, Koller O, Haram K (1982) Haemoconcentration in severe pre-eclampsia. Br J Obstet Gynaecol 89:802–805
Schmid-Schönbein H, Hugo R von, Rieger H (1976) Fließeigenschaften und Fließbedingungen bei gesteigerter Erythrozytenaggregation und Hyperkoagulabilität. In: Ludwig H, Kurz E (Hrsg) Ergebnisse der Angiologie, Bd 14: Die Beckenvenen. Schattauer, Stuttgart, S 205–221
Schröck R (1983) Hemodilution in gestosis: Indications - limitations. In: Janisch H, Reinold E (eds) Dilemmas in gestosis. Int. Symposium Vienna. Thieme, Thieme-Stratton, Stuttgart New York, pp 153–156
Schröck R, Heimisch W, Gebhard K, Mendler N (1981) Hyperonkotische Hämodilution beim schwangeren Schaf als Therapiemodell der EPH-Gestose. Z Geburtshilfe Perinatol 185:168–177
Siekmann U, Oggolter-Siekmann H, Heilmann L (1983) Prognostic value of raised red cell aggregation for the development of pregnancy-induced hypertension (PIH) (Abstr). Biorheology 3:271
Stuart MJ, Clark DA, Sunderji SG, Allen JB, Yambo T, Elrad H, Slott JH (1981) Decreased prostacyclin production: A characteristic of chronic placental insufficiency syndromes. Lancet 1:1126–1128
Sunder-Plassman L, Klövekorn WP, Holter K, Hase U, Messmer K (1971) The physiological significance of acutely induced hemodilution. Proc. 6th Eur. Conf. Microcir., Aalborg 1970. Karger, Basel, pp 23–31
Vane JR, Bunting S, Moncada S (1982) Prostacyclin in physiology and pathophysiology. Int Rev Exp Pathol 23:162–207
Weitz S, Borok Z, Owen J, Auerbach M, Nossel HL (1983) Fibrin proteolysis and platelet a-granule release in pre-eclampsia and eclampsia (Abstr). Thromb Haemost 50:322
Wengeler H, Holzgreve H, Gokel JM, Holzmann K (1976) Thrombotisch-thrombozytopenische Purpura (Moschkowitz-Syndrom) in der Schwangerschaft. Geburtshilfe Frauenheilkd 36:953–959
Ylikorkala O (1983) Prostacyclin and thromboxane during human pregnancy. Acta Obstet Gynecol Scand [Suppl] 113:51–53
Ylikorkala O, Kirkinen P, Viinikka L (1981) Maternal plasma prostacyclin concentration in preeclampsia and other pregnancy complications. Br J Obstet Gynaecol 88:968–972
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Graeff, H., von Hugo, R., Schröck, R. (1986). Neuere Aspekte der Hämostase, Hämatologie und Hämorheologie bei der schweren EPH-Gestose. In: Hossli, G., Frey, P., Kreienbühl, G. (eds) ZAK Zürich. Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine, vol 189. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71270-8_30
Download citation
DOI: https://doi.org/10.1007/978-3-642-71270-8_30
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16619-1
Online ISBN: 978-3-642-71270-8
eBook Packages: Springer Book Archive