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The Association of the Escherichia coli Chromosome with the Cell Membrane

  • Conference paper
Book cover Bacterial Chromatin

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

Abstract

The notion that the bacterial chromosome is attached to the membrane is by now firmly embedded in the folklore of bacterial structure. It is derived from a series of experiments on the segregation of the Escherichia coli chromosome and its plasmids, which Jacob et al. (1963) used for their original postulation of the replicon model. Unfortunately, in the subsequent years this notion remains more compelling for its logical appeal than for the rigorousness of the experimental evidence. In any case, this aspect of the replicon model has not contributed very much to our understanding of genome segregation or of the regulation of its synthesis. Despite this, no one so far has presented a serious alternative for the physical basis for chromosome segregation.

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Author information

Authors and Affiliations

  1. Department of Molecular Biology and Microbiology, Tufts University, Schools of Medicine, Veterinary Medicine and Dental Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA

    G. B. Ogden & M. Schaechter

Authors
  1. G. B. Ogden
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  2. M. Schaechter
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Editor information

Editors and Affiliations

  1. Department of Cell Biology, Laboratory of Genetics, University of Camerino, I-62032, Camerino (MC), Italy

    Claudio O. Gualerzi

  2. Max-Planck-Institut für Molekulare Genetik, Ihnestraße 73, D-1000, Berlin 33, Germany

    Claudio O. Gualerzi  & Cynthia L. Pon  & 

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© 1986 Springer-Verlag Berlin Heidelberg

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Ogden, G.B., Schaechter, M. (1986). The Association of the Escherichia coli Chromosome with the Cell Membrane. In: Gualerzi, C.O., Pon, C.L. (eds) Bacterial Chromatin. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71266-1_5

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  • DOI: https://doi.org/10.1007/978-3-642-71266-1_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71268-5

  • Online ISBN: 978-3-642-71266-1

  • eBook Packages: Springer Book Archive

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