The Membrane Trigger Hypothesis Revisited
A cardinal rule of modern scientific life, one which I have shamelessly violated, is that one should not write too many reviews. In this spirit, and fearing that Gunther Blobel and I were invited to spar in print here merely to promote book sales, I at first declined the kind invitation from the editors. However, they threatened to nominate me for service on an NIH study section. Thus, to minimize pain, I take pen in hand. What follows is not intended as a scholarly review, but rather opinions of the successes, and failures, of the membrane trigger hypothesis.
KeywordsEndoplasmic Reticulum Leader Sequence Leader Peptide Bacterial Plasma Membrane Nascent Chain
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