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The Membrane Trigger Hypothesis Revisited

  • B. Wickner
Conference paper
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 125)

Abstract

A cardinal rule of modern scientific life, one which I have shamelessly violated, is that one should not write too many reviews. In this spirit, and fearing that Gunther Blobel and I were invited to spar in print here merely to promote book sales, I at first declined the kind invitation from the editors. However, they threatened to nominate me for service on an NIH study section. Thus, to minimize pain, I take pen in hand. What follows is not intended as a scholarly review, but rather opinions of the successes, and failures, of the membrane trigger hypothesis.

Keywords

Endoplasmic Reticulum Leader Sequence Leader Peptide Bacterial Plasma Membrane Nascent Chain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bretscher MS (1973) Science 181: 622PubMedCrossRefGoogle Scholar
  2. Tanford C (1973) The hydrophobic effect. Wiley, New YorkGoogle Scholar
  3. Walter P, Blobel G (1981) J Cell Biol 91: 551PubMedCrossRefGoogle Scholar
  4. Wickner W (1979) Annu Rev Biochem 48: 23PubMedCrossRefGoogle Scholar
  5. Wickner W (1980) Science 210: 861PubMedCrossRefGoogle Scholar
  6. Wickner W, Lodish H, Science 230: 400Google Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1986

Authors and Affiliations

  • B. Wickner
    • 1
  1. 1.Department of Biological ChemistryUniversity of CaliforniaLos AngelesUSA

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