Abstract
Toxicological registration requirements for pesticides demand preferably dogs as animals of choice for non-rodent studies. In the GDR miniature swine of SPF-quality (MINI-LEWE) are available which are regarded as highly suitable for toxicological testing of pesticides. Their usefulness is due to the well-known similarities between man and swine with regard to anatomy and physiology, especially concerning the digestive tract, the kidney, the cardiovascular system and the skin and thus the organ systems engaged in resorption, distribution, and excretion. Table 1 shows the citation frequency of the use of minipigs and dogs in toxicicological studies 1982–1983.
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© 1986 Springer-Verlag
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Clausing, P., Beitz, H., Gericke, S., Solecki, R. (1986). On the Usefulness of Minipigs in Toxicology Testing of Pesticides. In: Chambers, C.M., Chambers, P.L., Tuomisto, J. (eds) Toxic Interfaces of Neurones, Smoke and Genes. Archives of Toxicology, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71248-7_40
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DOI: https://doi.org/10.1007/978-3-642-71248-7_40
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