Cardiodynamics During Rapid Volume Expansion and Function of Chronically Ischemic Myocardium Under Isoflurane: A Study in Chronically Instrumented Dogs

  • M. Zimpfer
  • N. Mayer
  • H. Gilly
  • E. Maurer
  • K. Steinbereithner
Conference paper
Part of the Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine book series (A+I, volume 185)


Volatile anesthetics have a negatively inotropic effect and therefore influence the function of the ischemic and nonischemic myocardium. It may also be assumed that the simultaneously induced peripheral vasodilatation has major consequences for the cardiodynamics during various forms of inhalation anesthesia [16, 28, 29]. It was the purpose of this study to examine the effects of increasing concentrations of isoflurane 1) on cardiodynamics under acute volume expansion and 2) on the contractile function of chronically ischemic myocardium on the basis of measurements of segmental left ventricular function.


Coronary Blood Flow Volatile Anesthetic Left Atrial Pressure Inhalation Anesthesia Regional Myocardial Function 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • M. Zimpfer
  • N. Mayer
  • H. Gilly
  • E. Maurer
  • K. Steinbereithner

There are no affiliations available

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