Skip to main content

Pharmacokinetic Profile of Isoflurane in Children

  • Conference paper
Book cover Isoflurane
  • 71 Accesses

Abstract

Although the factors governing the uptake and distribution of inhalation agents are the same in adults and children, the values of some physiological parameters and the pharmacological responses differ qualitatively. Consequently, the pharmacodynamics of inhalation agents must be expected to differ largely between adults and children.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Brandom BW, Brandom RB, Cook DR (1983) Uptake and distribution of halothane in infants: in vivo measurements and computer simulations. Anesth Analg 62: 404–410

    PubMed  CAS  Google Scholar 

  • Cameron CB, Robinson S, Gregory GA (1984) The minimum anesthetic concentration of isoflurane in children. Anesth Analg 63: 418–420

    PubMed  CAS  Google Scholar 

  • Eger EI, Saidman LJ, Brandstater B (1965) Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology 26:756 Eger

    Google Scholar 

  • Eger EI II, Bahlman SH, Munson ES (1971) The effect of age on the rate of increase of alveolar anesthetic concentration. Anesthesiology 35: 365–372

    Article  PubMed  CAS  Google Scholar 

  • Gregory GA, Eger EI II, Munson ES (1969) The relationship between age and halothane requirement in man. Anesthesiology 30: 488

    Article  PubMed  CAS  Google Scholar 

  • Lerman J, Robinson S, Willis MM, Gregory GA (1983) Anesthetic requirements for halothane in young children 0-1 month and 1-6 months of age. Anesthesiology 59: 421–424

    Article  PubMed  CAS  Google Scholar 

  • Lerman J, Gregory GA, Willis MM, Eger EI II (1984) Age and solubility of volatile anesthetics in blood. Anesthesiology 61: 139–143

    Article  PubMed  CAS  Google Scholar 

  • Pauca AL, Dripps RD (1973) Clinical experience with isoflurane ( Forane ). Br J Anaesth 45: 697–703

    Article  PubMed  CAS  Google Scholar 

  • Salanitre E, Rackow H (1969) The pulmonary exchange of nitrous oxide and halothane in infants and children. Anesthesiology 30: 388–394

    Article  PubMed  CAS  Google Scholar 

  • Sawyer DC, Eger EI II, Bahlman SH (1971) Concentration dependence of hepatic halothane metabolism. Anesthesiology 34: 230–235

    Article  PubMed  CAS  Google Scholar 

  • Sechzer PH, Linde HW, Dripps RD (1963) Uptake of halothane by the human body. Anesthesiology 24: 779–783

    Article  PubMed  CAS  Google Scholar 

  • Stevens WC, Dolan WM, Gibbon RT, White A, Eger EI II, Miller RD, De Jong RH, Elashoff RM (1975) Minimum alveolar concentration ( MAC) of isoflurane with and without nitrous oxide in patients of various age. Anesthesiology 42: 197

    Google Scholar 

  • Torri G, Damia G, Fabiani ML, Frova G (1972) Uptake and elimination of enflurane in man. Br J Anaesth 44: 789

    Article  PubMed  CAS  Google Scholar 

  • Torri G, Damia G, Fabiani ML (1974) Effect of nitrous oxide on the anaesthetic requirement of enflurane. Br J Anaesth 46: 468

    Article  PubMed  CAS  Google Scholar 

  • Wren WS (1984) Isoflurane in pediatrics. 8th World congress of anesthesiology. Symposium on isoflurane, proceedings, p 41

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Torri, G., Salvo, I., Righi, P., Calderini, E., Bordoli, W. (1986). Pharmacokinetic Profile of Isoflurane in Children. In: Lawin, P., Van Aken, H., Puchstein, C. (eds) Isoflurane. Anaesthesiology Intensive Care Medicine/Anaesthesiologie und Intensivmedizin, vol 182. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71230-2_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-71230-2_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16574-3

  • Online ISBN: 978-3-642-71230-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics