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Isoflurane pp 106-110 | Cite as

Cerebral Blood Flow with 1% Isoflurane

  • A. Vandesteene
  • V. Trempont
  • M. de Rood
  • M. Focroul
  • A. Schoutens
Conference paper
Part of the Anaesthesiology Intensive Care Medicine/Anaesthesiologie und Intensivmedizin book series (A+I, volume 182)

Abstract

The inhalation anesthetics are peripheral vasodilators and are reported to have the same effects on the cerebral vasculature, increasing cerebral blood flow (CBF) and cerebral blood volume (CBV), even at clinical concentrations [3, 7, 13, 15, 17]. This question is still debated [4, 5, 12].

Keywords

Cerebral Blood Flow Cerebral Perfusion Pressure Cerebral Blood Volume Minimum Alveolar Concentration Cerebral Vasculature 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Adams RW, Cucchiara RF, Gronert GA, Messick JM, Michenfelder JD (1981) Isoflurane and cerebrospinal fluid pressure in neurosurgical patients. Anesthesiology 54: 97–99PubMedCrossRefGoogle Scholar
  2. 2.
    Campkin TV (1984) Isoflurane and cranial extradural pressure. Br J Anaesth 56: 1083–1087PubMedCrossRefGoogle Scholar
  3. 3.
    Christensen MS, Hoedt-Rasmussen K, Lassen NA (1967) Cerebral vasodilatation by halothane anaesthesia in man and its potentiation by hypotension and hypercapnia. Br J Anaesth 39: 927–934PubMedCrossRefGoogle Scholar
  4. 4.
    de Rood M, Deloof T, Berre J, Verbist A, Fruhling J, Dang Phuoc T (1980) Effect of 1% enflurane anesthesia on cerebral blood flow and metabolism in neurosurgical patients during normo- and hyperventilation. Acta Anaesthesiol Belg 31 (Suppl): 3–19PubMedGoogle Scholar
  5. 5.
    de Rood M, Deloof T, Verbist A, Fruhling J (1980) Influence of 1% enflurane anesthesia on regional cerebral blood flow repartition under normo-and hyperventilation. Acta Anaesthesiol Belg 31 (Suppl): 29–41PubMedGoogle Scholar
  6. 6.
    Grosslight K, Foster R, Colohan AR, Bedford RF (1985) Isoflurane for neuroanesthesia: risk factors for increases in intracranial pressure. Anesthesiology 63: 533–536PubMedCrossRefGoogle Scholar
  7. 7.
    MacDowall G (1967) The effects of clinical concentrations of halothane on the blood flow and oxygen uptake of the cerebral cortex. Br J Anaesth 39: 186–196CrossRefGoogle Scholar
  8. 8.
    Murphy FL, Kennell EM, Johnstone RE, Lief PL, Jobes DR, Tompkins BM, Gutsche BB, Behar MG, Wollman H (1974) The effects of enflurane, isoflurane, and halothane on cerebral blood flow and metabolism in man. Abstracts of scientific papers, annual meeting of the American society of anesthesiologists, pp 61–62Google Scholar
  9. 9.
    Murphy FL, Kennel EM, Jobes DR, Gutsche BB, Wollman H (1975) The effects of forane on cerebral blood flow and metabolism in man. Isoflurane New Drug Application: 2386–2395Google Scholar
  10. 10.
    Obrist WD, Thompson HK, Shanwang H, Wilkinson WE (1975) Regional cerebral blood flow estimated by Xe 133 inhalation. Stroke 6: 245–256PubMedCrossRefGoogle Scholar
  11. 11.
    Risberg J, Ali Z, Wilson EM, Wills EL, Halsey JH (1975) Regional cerebral blood flow by Xe 133 inhalation. Stroke 6: 142–148PubMedCrossRefGoogle Scholar
  12. 12.
    Rolly G, Van Aken J (1979) Influence of enflurane on cerebral blood flow in man. Acta Anaesthesiol Scand 71 (Suppl): 59–63CrossRefGoogle Scholar
  13. 13.
    Sakabe T, Maekawa T, Fujii S, Ishikawa T, Tateishi A, Takishita H (1983) Cerebral circulation and metabolism during enflurane anesthesia in humans. Anesthesiology 59: 532–536PubMedCrossRefGoogle Scholar
  14. 14.
    Smith AL, Neigh JL, Hoffmann JC, Wollman H (1970) Effects of general anesthesia on autoregu- lation cerebral blood flow in man. J Appl. Physiol 29 (5): 665–669PubMedGoogle Scholar
  15. 15.
    Smith AL, Wollman H (1972) Cerebral blood flow and metabolism: effects of anesthetic drugs and techniques. Anesthesiology 36: 378–400PubMedCrossRefGoogle Scholar
  16. 16.
    Todd MM, Drummond JC, Shapiro HM (1982) Comparative cerebrovascular and metabolic effects of halothane, enflurane and isoflurane. Anesthesiology 57 (3): A 332Google Scholar
  17. 17.
    Wollman H, Alexander SC, Cohen PJ, Chase PE, Melman E, Behar MG (1964) Cerebral circulation of man during halothane anesthesia. Anesthesiology 25: 180–194PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • A. Vandesteene
  • V. Trempont
  • M. de Rood
  • M. Focroul
  • A. Schoutens

There are no affiliations available

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