How Do Volatile Agents Produce Anesthesia?

  • J. R. Trudell
Conference paper
Part of the Anaesthesiology Intensive Care Medicine/Anaesthesiologie und Intensivmedizin book series (A+I, volume 182)


Nearly all of the molecular mechnisms of inhalation anesthesia reviewed here will be very general in their applicability. This generality is required because inhalation anesthetics have important effects in muscles, vascula walls, and components of many tissues, and not only the brain and central nervous system. Despite years of effort with techniques such as selective brain lesions, applications of stimulating currents, injections of neurotransmitters, or measurement of local rates of glucose utilization [1, 2], it is still not known in which principal region of structure in the brain anesthesia occurs.


Malignant Hyperthermia Phospholipid Bilayer Adenylate Kinase Inhalation Anesthesia Inhalation Anesthetic 
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© Springer-Verlag Berlin Heidelberg 1986

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  • J. R. Trudell

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