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Tissue Oxygen Pressure in Ulcers of the Lower Leg

  • A. Creutzig
  • T. Wuppermann
  • U. Hanauske
  • K. Alexander
Conference paper

Abstract

The development of leg ulcers is attributed to disturbed skin microcirculation, which is said to be the result of an increase in capillary pressure with the leaking of blood components through the capillary wall and the formation of a specific microedema [5]. Transcutaneous oxygen pressure measurements in the vicinity of ulcers yielded low values in both venous and arterial ulcers [1]. This is explained by a rarefication of capillaries [8]. In contrast, patients with liposclerosis or venous ulcerations show a marked proliferation of capillaries in the subcutaneous tissue [3]. Around the capillaries, fibrin walls are found, which act as diffusion barriers for oxygen [2]. Local hyperemia is observed after positron emission tomography and measurements of the blood flow in the skin using the laser-Doppler method [7, 10]. We have determined the tissue oxygen pressure in leg ulcers.

Keywords

Capillary Pressure Venous Ulceration Chronic Venous Insufficiency Compression Bandage Arterial Ulcer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Borzykowski, M., B. Krähenbühl: Mesure non invasive de l’oxygénation cutanée en cas d’ulcères chroniques des membres inférieurs. Schweiz, med. Wschr. 111 (1981) 1972–1974Google Scholar
  2. 2.
    Browse, N.L., K. G. Burnand: The cause of venous ulceration. Lancet 2 (1982) 243–245PubMedCrossRefGoogle Scholar
  3. 3.
    Burnand, K. G., I. Whimster, G. Clemenson, L. M. Thomas, N. L. Browse: The relationship between the number of capillaries in the skin of the venous ulcer-bearing area of the lower leg and the fall in foot vein pressure during exercise. Br. J. Surg. 68 (1981) 297–300PubMedCrossRefGoogle Scholar
  4. 4.
    Creutzig, A., W. Wrabetz, M. Lux, K. Alexander: Muscle tissue oxygen pressure in patients with arterial occlusive disease. Microvase. Res. 29 (1985) 350–359CrossRefGoogle Scholar
  5. 5.
    Fagrell, B.: Die gestörte Hautmikrozirkulation als Ursache venöser Ulcéra cruris. In: Trübestein, G. (Hrsg.): Arterielle Verschlußkrankheit und tiefe Venenthrombose. Thieme-Verlag, Stuttgart/New York (1984) S. 212–215Google Scholar
  6. 6.
    Hauss, J., K. Schönleben, H. U. Spiegel: Therapiekontrolle durch Überwachung des GewebePO2. Huber-Verlag, Bern (1982)Google Scholar
  7. 7.
    Hopkins, N. F., T. J. Spinks, C. G. Rhodes, A. C. Ranicar, C. W. Jamieson: Positron emission tomography in venous ulceration and liposclerosis: study of regional tissue function. Brit. med. J. 286 (1983)333–336Google Scholar
  8. 8.
    Huch, A., U. K. Franzeck, R. Huch, A. Bollinger: A. transparent transcutaneous oxygen electrode for simultaneous studies of skin capillary morphology, flow dynamics and oxygenation. Int. J. Microcirc.: Clin. Exp. 2 (1983), 103–108Google Scholar
  9. 9.
    Lübbers, D. W.: The meaning of the tissue oxygen distribution curve and its measurement by means of Pt-electrodes. Progr. Resp. Res. 3 (1969) 112–123Google Scholar
  10. 10.
    Partsch, H.: Hyperaemic hypoxia in venous ulceration. Br. J. Derm. 110 (1984) 249–251CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • A. Creutzig
  • T. Wuppermann
  • U. Hanauske
  • K. Alexander

There are no affiliations available

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