Abstract
In man, cirrhosis with portosystemic shunting as a consequence of portal hypertension produces changes of systemic circulation, i.e. hyperdynamic circulatory syndrome, which are characterized by decreased peripheral vascular resistance as well as increased cardiac output, systolic ejection rate, and intrapulmonary venous admixture [4, 11, 12]. In addition, changes of renal perfusion, i.e., hyperperfusion of the medulla with diminished perfusion of the cortex, have been demonstrated. Functional renal failure as a consequence of decompensated cirrhosis (i.e., so-called hepatorenal syndrome) have been partially attributed to these intrarenal perfusion changes [8].
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Baehmann, E., J. Lindner, K. Grasedyck, R. Eurich: Rattenleberkollagen bei protrahierter Thioacetamidintoxikation. Arzneim. Forsch./Drug Res. 28 (1960) 2260
Brodehl, J.: Thioacetamid in der Leberforschung. Klin. Wschr. 39 (1961) 956
Conn, H.O.: Rational approach to the hepatorenal syndrom. Gastroenterol. 65 (1973) 321
Gordon, M. J., L. R. M. Del Guercio: Late effects of portal systemic shunting procedures on cardiorespiratory dynamics in man. Ann. Surg. 176 (1972) 672
Grün, M., H. Liehr, H. Thiel, U. Rasenack: Effekt einer Endotoxinämie auf die renale und in-trarenale Hämodynamik bei Ratten mit und ohne portokavale Anastomose. Z. Gastroenterol. 76 (1976) 285
Heinrich, R., W. Grauer, H. Schomerus, M. Günderoth, M. Kessler, J. Höper: Measurements of local pO2 in resting skeletal muscle of rats with portocaval anastomosis (PCA) under normoxic conditions. In: Oxygen Transport to Tissue V I Plenum. Publishing Corporation 1985
Kessler, M., D. W. Lübbers: Aufbau und Anwendungsmöglichkeiten verschiedener pO2-Elektroden. Pflüg. Arch. 291 (1966) 82
Kew Mc, P. W. Brunt, R. R. Varma, K. J. Hourigan, H. S. Williams, S. Sherlock: Renal and intrarenal blood-flow in cirrhosis of the liver. Lancet II (1971) 504
Lee, S. H., B. Fisher: Portocaval shunt in the rat. Surgery 50 (1961) 6668
Liehr, H., M. Grün, H. Thiel: Hepatic blood flow and cardiac output after portocaval anastomosis in the rat. Acta Hepato-Gastroenterol. 23 (1976) 31
Liehr, H., M. Grün, H. Thiel: Systemische Zirkulation bei portaler Hypertension. Verh. Ges. Inn. Med. 82 (1976) 159
Schomerus, H., I. Buchta, H. Arndt: Pulmonary function studies on oxygen transfer in patients with liver cirrhosis and different degree of portosystemic encephalopathy. Respiration 32 (1976) 1
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Heinrich, R. et al. (1987). PO2 Distribution in Muscle and Renal Cortex of Rats with Chronic Liver Changes. In: Ehrly, A.M., Hauss, J., Huch, R. (eds) Clinical Oxygen Pressure Measurement. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71226-5_31
Download citation
DOI: https://doi.org/10.1007/978-3-642-71226-5_31
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-71228-9
Online ISBN: 978-3-642-71226-5
eBook Packages: Springer Book Archive