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Acute Leukemias pp 418–422Cite as

Surface Marker Analysis by Monoclonal Antibodies: A Valuable Technique in Childhood Acute Myeloid Leukemia

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Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 30))

Abstract

A considerable number of monoclonal antibodies (MoAbs) with myeloid activity have been described during the last few years (summarized in [1]). These MoAbs have been applied to the study of normal myeloid differentiation, as well as to the surface marker analysis of acute myeloid leukemia (AML) [2–6]. Although there is a strong tendency for morphological differentiation to correspond to surface antigen differentiation of malignant myeloid cells [2, 3], a recent report has failed to correlate the FAB classification system with immunologic categories of AML [6].

Supported in part by the Deutsche Krebshilfe.

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Author information

Authors and Affiliations

  1. Departments of Hematology/Oncology, Klinikum Steglitz, Berlin, Germany

    W. D. Ludwig & A. Gatzke

  2. Departments of Hematology/Oncology, University of Mainz, Germany

    F. Herrmann

  3. Departments of Pediatrics, University of Hannover, Germany

    M. Budde

  4. Departments of Pediatrics, University of Münster, Federal Republic of Germany

    U. Creutzig, J. Ritter & G. Schellong

Authors
  1. W. D. Ludwig
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  2. F. Herrmann
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  3. A. Gatzke
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  4. M. Budde
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  5. U. Creutzig
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  6. J. Ritter
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  7. G. Schellong
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Editor information

Editors and Affiliations

  1. Departments of Internal Medicine and Pediatrics, University of Münster, Albert-Schweitzer-Strasse 33, D-4400, Münster, Federal Republic of Germany

    T. Büchner , G. Schellong , W. Hiddemann , D. Urbanitz  & J. Ritter , , ,  & 

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© 1987 Springer-Verlag Berlin Heidelberg

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Ludwig, W.D. et al. (1987). Surface Marker Analysis by Monoclonal Antibodies: A Valuable Technique in Childhood Acute Myeloid Leukemia. In: Büchner, T., Schellong, G., Hiddemann, W., Urbanitz, D., Ritter, J. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71213-5_73

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  • DOI: https://doi.org/10.1007/978-3-642-71213-5_73

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16556-9

  • Online ISBN: 978-3-642-71213-5

  • eBook Packages: Springer Book Archive

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