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Surface Marker Analysis by Monoclonal Antibodies: A Valuable Technique in Childhood Acute Myeloid Leukemia

  • W. D. Ludwig
  • F. Herrmann
  • A. Gatzke
  • M. Budde
  • U. Creutzig
  • J. Ritter
  • G. Schellong
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 30)

Abstract

A considerable number of monoclonal antibodies (MoAbs) with myeloid activity have been described during the last few years (summarized in [1]). These MoAbs have been applied to the study of normal myeloid differentiation, as well as to the surface marker analysis of acute myeloid leukemia (AML) [2–6]. Although there is a strong tendency for morphological differentiation to correspond to surface antigen differentiation of malignant myeloid cells [2, 3], a recent report has failed to correlate the FAB classification system with immunologic categories of AML [6].

Keywords

Acute Myeloid Leukemia Acute Leukemia Acute Myeloblastic Leukemia Childhood Acute Myeloid Leukemia Surface Marker Analysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • W. D. Ludwig
    • 1
  • F. Herrmann
    • 2
  • A. Gatzke
    • 1
  • M. Budde
    • 3
  • U. Creutzig
    • 4
  • J. Ritter
    • 4
  • G. Schellong
    • 4
  1. 1.Departments of Hematology/OncologyKlinikum SteglitzGermany
  2. 2.Departments of Hematology/OncologyUniversity of MainzGermany
  3. 3.Departments of PediatricsUniversity of HannoverGermany
  4. 4.Departments of PediatricsUniversity of MünsterFederal Republic of Germany

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