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Therapy Results in Five ALL-BFM Studies Since 1970: Implications of Risk Factors for Prognosis

  • H. Riehm
  • H.-J. Feickert
  • M. Schrappe
  • G. Henze
  • G. Schellong
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 30)

Abstract

Prognosis in childhood acute lymphoblastic leukemia (ALL) after risk-adapted therapy is first of all dependent on the quality of therapy. Conventional risk factors such as WBC, age, sex, organ involvement, and other features certainly have lost their prognostic significance in varying degrees during the evolution of risk-adapted and necessarily intensive therapy. Still, the tumor burden and other ill-defined or unknown factors are responsible for therapy failure. Obviously, the patient group with therapy failure must be the target of future efforts.

Keywords

Acute Lymphoblastic Leukemia Medium Risk Childhood Acute Lymphoblastic Leukemia Late Responder Complete Continuous Remission 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • H. Riehm
    • 1
  • H.-J. Feickert
    • 1
  • M. Schrappe
    • 1
  • G. Henze
    • 2
  • G. Schellong
    • 3
  1. 1.Department of PediatricsHannover Medical SchoolHannoverGermany
  2. 2.Department of PediatricsBerlin Free UniversityGermany
  3. 3.Department of PediatricsMünster UniversityFederal Republic of Germany

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