Abstract
A cell lineage affected by acute leukemia is distinguished from the corresponding normal lineage by a prevalence of immature blast cells and a deficit of mature cells. Currently there are two different concepts of antileukemic therapy that might profit from a clearer understanding of the causes of the excess of blast cells. These concepts are either to sweep out the leukemic cells by cytotoxic treatment, or to induce them to differentiate in a fashion like normal cells. We are interested to know if cell kinetics can add to this understanding.
This study was supported by the Deutsche Forschungsgemeinschaft: Do 184/2-3.
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© 1987 Springer-Verlag Berlin Heidelberg
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Dörmer, P., Ucci, G., Hershko, C., Wilmanns, W. (1987). Cell Kinetics in Leukemia and Preleukemia. In: Büchner, T., Schellong, G., Hiddemann, W., Urbanitz, D., Ritter, J. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71213-5_1
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DOI: https://doi.org/10.1007/978-3-642-71213-5_1
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