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Abstract

Neuroblastoma sympathicum is a tumor typically occurring during childhood. It derives from embryonic cells of the neural crest and frequently originates from the ganglion cells of the sympathetic chain and the adrenal medulla.

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References

  1. Albert RW (1981) Esthesioneuroblastoma. Ear Nose Throat J 60: 522

    PubMed  CAS  Google Scholar 

  2. Allen RW, Ogden B, Bentley F, Jung AL (1980) Fetal hydantoin syndrome, neuroblastoma, and hemorrhagic disease in a neonate. JAMA 244: 1464

    Article  PubMed  Google Scholar 

  3. Bachmann K-D (1962) Das Neuroblastoma sympathicum. Klinik und Prognose von 1030 Fällen. Z Kinderheilkd 86: 710

    Article  PubMed  CAS  Google Scholar 

  4. Bachmann K-D (1971) Tumoren des sympathischen Nervensystems. In: Opitz H, Schmid F (eds) Handbuch der Kinderheilkunde, vol 8, 2nd edn. Springer, Berlin Heidelberg New York

    Google Scholar 

  5. Bachmann K-D, Friedmann G (1967) Schädelmetastasen beim Neuroblastom mit bevorzugter Absiedlung im Nahtbereich. Fortschr Röntgenstr 106: 422

    Article  CAS  Google Scholar 

  6. Balakrishnan V, Rice MS, Simpson DA (1974) Spinal neuroblastomas. Diagnosis, treatment and prognosis. J Neurosurg 40: 631

    Article  PubMed  CAS  Google Scholar 

  7. Berthold F (1985) Current concepts on the biology of neuroblastoma. Blut 30: 65

    Article  Google Scholar 

  8. Bill AH, Morgan A (1970) Evidence for immune reactions to neuroblastoma and future possibilities for investigation. J Pediatr Surg 5: 111

    Article  PubMed  CAS  Google Scholar 

  9. Boltshauser E, Deonna Th, Hirt HR (1979) Myoclonic encephalopathy of infants or “dancing eyes syndrome”. Helv Paediatr Acta 34: 119

    PubMed  CAS  Google Scholar 

  10. Brodeur GM (1982) Genetics and cytogenetics of human neuroblastoma. In: Pochedly C (ed) Neuroblastoma. Elsevier Biochemical, New York

    Google Scholar 

  11. Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM (1984) Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 224: 1121

    Article  PubMed  CAS  Google Scholar 

  12. Burkes EJ, Kelly DE, Hill C (1980) Primary mandibular neuroblastoma. J Oral Surg 38: 131

    Google Scholar 

  13. Carvalho L (1973) Spontaneous regression of an untreated neuroblastoma. Br J Ophthalmol 57: 832

    Article  PubMed  CAS  Google Scholar 

  14. D’Angio GJ, Evans AE, Koop CE (1971) Special pattern of widespread neuroblastoma with favorable prognosis. Lancet 1: 1046

    Article  PubMed  Google Scholar 

  15. De Lorimier AD, Bragg KU, Linden G (1969) Neuroblastoma in childhood. Am J Dis Child 118: 441

    Google Scholar 

  16. Dosik GM, Rodriguez V, Benjamin RS, Bodey GP (1978) Neuroblastoma in the adult. Cancer 41: 56

    Article  PubMed  CAS  Google Scholar 

  17. Evans AE, Hummeler K (1973) The significance of primitive cells in marrow aspirates of children with neuroblastoma. Cancer 32: 906

    Article  PubMed  CAS  Google Scholar 

  18. Evans AE, D’Angio GJ, Randolph J (1971) A proposed staging for children with neuroblastoma. Cancer 27: 374

    Article  PubMed  CAS  Google Scholar 

  19. Evans AE, Blore J, Hadley R, Tanindi S (1971) The La Brosse spot test: a practical aid in the diagnosis and management of children with neuroblastoma. Pediatrics 47: 913

    PubMed  CAS  Google Scholar 

  20. Evans AE, Chatten J, D’Angio GJ, Gerson JM, Robinson J, Schnaufer L (1980) A review of 17 IV-S Neuroblastoma patients of the Children’s Hospital of Philadelphia. Cancer 45: 833

    Article  PubMed  CAS  Google Scholar 

  21. Förster C, Weinmann H (1971) Symptomatische infantile Polymyoclonie. Monatsschr Kinderheilkd 111: 240

    Google Scholar 

  22. Franklin JM, Pritchard J (1983) Detection of bone marrow invasion by neuroblastoma is improved by sampling at two sides with both aspirates and trephine biopsies. J Clin Pathol 36: 1215

    Article  PubMed  CAS  Google Scholar 

  23. Gilbert F, Balaban G, Brangman D, Herrmann N, Lister A (1983) Homogeneously staining regions and tumorigenicity. Int J Cancer 31: 765

    Article  PubMed  CAS  Google Scholar 

  24. Gitlow StE, Dziedzic LB, Dziedzic StW (1982) Patterns of catecholamine metabolism in neuroblastoma. In: Pochedly C (ed) Neuroblastoma. Elsevier Biochemical, Amsterdam

    Google Scholar 

  25. Gordes W, Fischer V (1973) Intraspinales Neuroblastom im Kindesalter. Arch Orthop Unfallchir 77: 236

    Article  PubMed  CAS  Google Scholar 

  26. Goldman A, Vivian G, Gordon Pritchard J, Kemshead J (1984) Immunolocalization of neuroblastoma using ra-diolabeled monoclonal antibody UJ 13 A. J Pediatr 105: 252

    Article  PubMed  CAS  Google Scholar 

  27. Hamilton AE, Rubenstein LJ, Poole GJ (1973) Primary intracranial esthesioneuroblastoma (olfactory neuroblastoma). J Neurosurg 38: 548

    Article  PubMed  CAS  Google Scholar 

  28. Hann HL, Evans AE, Cohen IJ, Leitmeyer BA (1981) Biologic differences between neuroblastoma stages IV-S and IV: measurement of serum ferritin and E-rosette inhibition in 30 children. N Engl J Med 305: 425

    Article  PubMed  CAS  Google Scholar 

  29. Hann HL, Levy HW, Evans AE (1980) Serum ferritin as a guide to therapy in neuroblastoma. Cancer Res 40: 1411

    PubMed  CAS  Google Scholar 

  30. Harms D, Wilke H (1977) Pathologische Anatomie des Neuroblastoms. Z Kinderchirurg 22: 122

    Google Scholar 

  31. Hecht F, Kaiserhecht B, Northrup SC (1982) Genetics of familial neuroblastoma: long range studies. Cancer Genet Cytogenet 7: 227

    Article  PubMed  CAS  Google Scholar 

  32. Hellström I, Hellstrom KE, Bill AH, Pierce GE, Yong JPS (1970) Studies on cellular immunity to human neuroblastoma cells. Int J Cancer 6: 172

    Article  PubMed  Google Scholar 

  33. Hughes M, Mardsen HB, Palmer MK (1974) Histologic patterns of neuroblastoma related to prognosis and clinical staging. Cancer 34: 1706

    Article  PubMed  CAS  Google Scholar 

  34. Ishiguro Y, Kato K, Ito T, Nagaya M, Yamada N, Sugito T (1983) Nervous system specific enolase in serum as a marker for neuroblastoma. Pediatrics 72: 696

    PubMed  CAS  Google Scholar 

  35. Jaffe N, Cassady JR, Filler RM, Petersen R, Traggis D (1975) Heterochromia and Horner syndrome associated with cervical and mediastinal neuroblastoma. J Pediatr 87: 75

    Article  PubMed  CAS  Google Scholar 

  36. Johnsonbough RE, Cahill R (1975) Screening procedures for neuroblastoma: false-negative results. Pediatrics 56: 267

    Google Scholar 

  37. Käser H (1972) Biochemische Diagnostik des Phaochromozytoms, des Neuroblastoms und anderer neuroektodermaler Neoplasien. Helv Paediatr Acta [Suppl] 29: 1

    Google Scholar 

  38. Käser H, Wagner HP, Zuppinger K, Zurbriigg R (1974) Zur biochemischen Tumordiagnostik im Kindesalter. Schweiz Med Wochenschr 104: 642

    PubMed  Google Scholar 

  39. Kaufman RA, Thrall JH, Keyes JW, Braun ML, Zakem JF (1978) False-negative bone scans in neuroblastoma metastatic to the ends of long bones. AJR 130: 131

    PubMed  CAS  Google Scholar 

  40. Kiess W, Linderkamp O, Hadorn H-B, Haas R (1984) Fetal alcohol syndrome and malignant disease. Eur J Pediatr 143: 160

    Article  PubMed  CAS  Google Scholar 

  41. Kimmig B, Brandeis WE, Adolph J (1985) Diagnose und Therapiekontrolle des Neuroblastoms mit meta-Jod-Benzylguanidin. Dtsch Med Wochenschr 110: 175

    Article  PubMed  CAS  Google Scholar 

  42. Krivit W, Mirkin BL, Freier E, Nesbit U, Cooper NJ (1980) Serum catecholamine metabolites in stage IV neuroblastoma. In: Evans AE (ed) Advances in neuroblastoma research. Raven, New York

    Google Scholar 

  43. Kurz R, Mutz J, Pichler E (1977) Neuroblastom: Diagnose, Therapie und Prognose an Hand von 56 Patienten. Wien Klin Wochenschr [Suppl 67] 89: 16

    Google Scholar 

  44. Lampert F (1984) Neuroblastom. In: Kornhuber B (ed) Onkologie Padiatrie. Weiter- und Fortbildung, p 89 Springer, Berlin Heidelberg New York

    Google Scholar 

  45. Lampert F, Dietmair E (1973) Leukozyten-Adhärenz-Inhibition: ein einfacher in vitro-Test zum Nachweis tumorspezifischer Immunität und blockierender Serumfaktoren bei Kindern mit Malignomen. Infection 1: 17

    Article  PubMed  CAS  Google Scholar 

  46. Lang WE, Siegel SE, Shaw KNF et al. (1978) Initial urinary catecholamine metabolite concentrations and prognosis in neuroblastoma. Pediatrics 62: 77

    Google Scholar 

  47. Lauder I, Aherne W (1972) The significance of lymphocytic infiltration in neuroblastoma. Br J Cancer 26: 321

    Article  PubMed  CAS  Google Scholar 

  48. Leape LL, Lowmann JT, Loveland GC (1978) Multifocal nondisseminated neuroblastoma. J Pediatr 92: 75

    Article  PubMed  CAS  Google Scholar 

  49. Lee J AH (1976) Summer and death from neuroblastoma. Br Med J 11: 404

    Google Scholar 

  50. Lopezibor B, Schwartz AD (1985) Neuroblastoma. Pediatr Clin North Am 32: 755

    CAS  Google Scholar 

  51. MacKay B, Luna MA, Butler JJ (1976) Adult neuroblastoma electron microscopic observations in nine cases. Cancer 37: 1334

    Article  PubMed  CAS  Google Scholar 

  52. Margueritte G, Galifer RB, Pons JG (1982) Neuroblastoma of the pancreas in a two year old boy. In: Rayband G, Clement R, Lebrenil G (eds) Pediatric oncology. International congress series 570: 66 Excerpta Medica, Amsterdam

    Google Scholar 

  53. McKenzie CG, Hope-Stone HF (1975) Multiple adenomas of the thyroid occurring 20 years after successful radiotherapy of neuroblastoma in the cervical lymphnodes. Br J Radiol 48: 1028

    Article  PubMed  CAS  Google Scholar 

  54. McLaughlin JE, Urich H (1977) Maturing neuroblastoma and ganglioneuroblastoma: a study of four cases with long survival. J Pathol 121: 19

    Article  PubMed  CAS  Google Scholar 

  55. Miller RW (1977) Ethnic differences in cancer occurrence: genetic and environmental influences with particular reference to neuroblastoma. In: Mulvihill JJ, Miller RW, Fraumeni JF Jr (eds) Genetics of human cancer. Raven, New York, p 169

    Google Scholar 

  56. Moorhead PS, Evans AE (1980) Chromosomal findings in neuroblastoma patients and families. In: Evans AE (ed) Advances in neuroblastoma research. Raven, New York, p 132

    Google Scholar 

  57. Murray MR, Stout AP (1948) Sympathetic ganglioneuroblastoma cultivated in vitro. Cancer 1: 242

    Article  PubMed  CAS  Google Scholar 

  58. Oseas RS, Siddiqui AS, Wellman HN et al. (1982) Use-fullness of bone marrow imaging in childhood malignancies. J Pediatr 101: 206

    Article  PubMed  CAS  Google Scholar 

  59. Pegelow GH, Ebbin AJ, Powars D, Towner JW (1975) Familial neuroblastoma. J Pediatr 87: 763

    Article  PubMed  CAS  Google Scholar 

  60. Prasad KN, Zambernard J, Lasher R, Vanwoert MH (1970) Transmission of mouse neuroblastoma by a cell- free extract. Nature 228: 997

    Article  PubMed  CAS  Google Scholar 

  61. Punt J, Pritchard J, Pincott JR, Till K (1980) Neuroblastoma: a review of 21 cases presenting with spinal cord compression. Cancer 45: 3095

    Article  PubMed  CAS  Google Scholar 

  62. Quinn J J, Altmann AJ, Frantz CN (1980) Serum lactic dehydrogenase, an indicator of tumor activity in neuroblastoma. J Pediatr 97: 89

    Article  PubMed  CAS  Google Scholar 

  63. Raney RB, Lyon GM, Porter FS (1976) Neuroblastoma simulating acute leukemia. J Pediatr 89: 433

    Article  PubMed  Google Scholar 

  64. Reynolds CP, Smith RG, Frenkel EP (1981) The diagnosis dilemma of the “small round cell neoplasm”. Cancer 48: 2088

    Article  PubMed  CAS  Google Scholar 

  65. Ricour C, Duhamel JF, Lesec G, Schweisguth O (1977) Diarhee choleriforme dans un cas de ganglioneuroblastome. Arch Franc Pediatr 34: 552

    CAS  Google Scholar 

  66. Robinson R (1980) Tumors that secrete catecholamines. Wiley, Chichester

    Google Scholar 

  67. Robinson MJ, Howard RN (1969) Neuroblastoma presenting as myasthenia gravis in a child aged 3 years. Pediatrics 43: 111

    PubMed  CAS  Google Scholar 

  68. Romansky SG, Crocker DW, Shaw KNF (1978) Ultra-structural studies of neuroblastoma. Evaluation of cyto-differentiation and correlation of morphology and biochemical and survival data. Cancer 42: 2392

    Article  PubMed  CAS  Google Scholar 

  69. Seeger RC (1982) Immunology of neuroblastoma. In: Pochedly C (ed) Neuroblastoma. Elsevier Biochemical, New York

    Google Scholar 

  70. Siegel SE, Lang WE, Hanlow PJ et al. (1980) Patterns of urinary catecholamine excretion in neuroblastoma. In: Evans AE (ed) Advances in neuroblastoma research. Raven, New York, p 25

    Google Scholar 

  71. Stowens D (1957) Neuroblastoma and related tumors. Arch Pathol 63: 451

    CAS  Google Scholar 

  72. Sty JR, Kun LE, Casper JT (1980) Bone imaging as a diagnostic aid in evaluating neuroblastoma. Am J Pediatr Hematol Oncol 2: 115

    Google Scholar 

  73. Sugimoto T, Sawada T, Kusunoki T (1979) Immunological and biochemical studies on the carcinoembryonic antigen-like substance in human neuroblastoma. Pediatr Res 13: 91

    Article  PubMed  CAS  Google Scholar 

  74. Trump DL, Livingston JN, Baylin SB (1977) Watery diarrhea syndrome in an adult with ganglioneuroma- phaeochromocytoma. Cancer 40: 1526

    Article  PubMed  CAS  Google Scholar 

  75. Voute PA, Voss A, Delemarre JFM et al. (1980) The persistent challenge of neuroblastoma. In: Van Eys J, Sullivan MP (eds) Status of curability of childhood cancer. Raven, New York, p 145

    Google Scholar 

  76. Voute PA, van Putten WJ, Burgers JMV (1975) Tumors of the sympathetic nervous system. In: Bloom HJG, Lemerle J, Neidhardt MK, Voute PA (eds) Cancer in children. Springer, Berlin Heidelberg New York, p 138

    Google Scholar 

  77. Weng J J, Sinks LF, Chu TM (1974) Carcinoembryonic antigen in patients with neuroblastoma. J Surg Oncol 6: 211

    Article  Google Scholar 

  78. Williams Th E, Donaldson MH (1973) Neuroblastoma. In: Sutow WW, Vielti TJ, Fernbach DJ (eds) Clinical pediatric oncology. Mosby, St. Louis, p 506

    Google Scholar 

  79. Winkler K (1976) Paraneoplastische Symptome bei Neuroblastom. Monatsschr Kinderheilkd 124: 527

    PubMed  CAS  Google Scholar 

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© 1987 Springer-Verlag Berlin Heidelberg

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Dominick, H.C., Bachmann, KD. (1987). Neuroblastoma. In: Löhr, E., Leder, LD. (eds) Renal and Adrenal Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71207-4_14

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  • DOI: https://doi.org/10.1007/978-3-642-71207-4_14

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