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Expression of T-Cell Receptor by a Mouse Monoclonal Antigen-Specific Suppressor T-Cell Line

  • L. Adorini
  • G. Palmieri
  • A. Sette
  • E. Appella
  • G. Doria
Conference paper
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 126)

Abstract

The antigen receptor expressed by mouse T lymphocytes is composed of a disul- fide-linked dimer of about 85K, resolved under reducing conditions in two sub-units with an apparent Mr of approximately 42K (Allison et al. 1982; Kappler et al. 1983). The antigen-specific receptor expressed by human T lymphocytes displays a similar structure, but the two subunits, denominated α and β chain, have a Mr of about 51K and 43K, respectively (Meuer et al. 1983; Acuto et al. 1983).

Keywords

Suppressive Activity Antigen Receptor Antipeptide Antibody Parathymic Lymph Node Afferent Phase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • L. Adorini
    • 1
  • G. Palmieri
    • 1
  • A. Sette
    • 1
  • E. Appella
    • 2
  • G. Doria
    • 1
  1. 1.Laboratory of Pathology, CRE CasacciaENEA-Euratom Immunogenetics GroupRome A.DItaly
  2. 2.Laboratory of Cell BiologyNCI, NIHBethesdaUSA

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