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Functional Analysis of a Self-I-A Reactive T-Cell Clone Which Preferentially Stimulates Activated B Cells

  • T. Saito
  • K. Rajewsky
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 126)

Abstract

Autoreactive T cells have been isolated in the form of continuously growing lines (Zauderer et al. 1984; Clayberger et al. 1984; Kimoto et al. 1984; Finnegan et al. 1984) or hybridomas (Glimcher and Shevach 1982; Rock and Benacerraf 1983, Endres et al. 1983; Nagase et al. 1984). Such T cells may participate in syngeneic mixed lymphocyte reaction (reviewed by Battisto and Ponzio 1981). However, it is not clear whether they play a regulatory role under physiological conditions (Hausman and Stobo 1979; Smith and Knowlton 1979; Lattime et al. 1981; Goto and Zvaifler 1983).

Keywords

Keyhole Limpet Hemocyanin Helper Function Autologous Mixed Lymphocyte Reaction Syngeneic Spleen Cell Splenic Adherent Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • T. Saito
    • 1
  • K. Rajewsky
    • 1
  1. 1.Institute for GeneticsUniversity of CologneCologneGermany

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