T-Cell Reactivity to Polymorphic MHC Determinants I. MHC-Guided T-Cell Reactivity

  • J. Reimann
  • K. Heeg
  • D. Kabelitz
  • H. Wagner
  • R. G. Miller
Conference paper
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 126)


The function of major histocompatibility complex (MHC) molecules remains elusive. Our detailed knowledge of their structural (genetic and biochemical) features contrasts sharply with our essentially speculative ideas concerning their function(s), which furthermore seem at present to be locked into sets of mutually exclusive hypotheses.


Major Histocompatibility Complex Major Histocompatibility Complex Molecule Allelic Major Histocompatibility Complex Major Histocompatibility Complex Haplotype Clonal Selection Theory 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • J. Reimann
    • 1
  • K. Heeg
    • 1
  • D. Kabelitz
    • 1
  • H. Wagner
    • 1
  • R. G. Miller
    • 2
  1. 1.Institute of Medical Microbiology and ImmunologyUniversity of UlmUlmGermany
  2. 2.Ontario Cancer InstituteTorontoCanada

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