Abstract
In this section many facts and possibly artifacts concerning short- and long-term cultured T-cell clones are presented and attempts are made to extrapolate to the in vivo significance. The function of T cells can only be measured after their activation. There is no single-cell assay for most T-cell functions. Consequently the function of the progeny of a single cell is being analyzed. This, however, puts constraints on the validity of the analysis, since cells have to be expanded in vitro under conditions which may or may not deter the functional potential present in the ancestor cells.
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© 1986 Springer-Verlag Berlin Heidelberg
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von Boehmer, H. (1986). Introductory Remarks. In: Fleischer, B., Reimann, J., Wagner, H. (eds) Specificity and Function of Clonally Developing T Cells. Current Topics in Microbiology and Immunology, vol 126. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71152-7_10
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DOI: https://doi.org/10.1007/978-3-642-71152-7_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-71154-1
Online ISBN: 978-3-642-71152-7
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