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Amniotic fluid cell and chorionic villi culture for prenatal HLA-determination

  • Lars O. Vejerslev
  • Hanna E. Hansen
  • Jes G. Westergaard
  • Finn Søndergaard
Conference paper
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 1)

Abstract

HLA-determination on placental or fetal tissue are of interest in Forensic Medicin as well as in Medical Genetics.I Forensic Medicine prenatal HLA-determination of the fetus supports a paternity diagnosis. In Medical Genetics one important aspect is prenatal diagnosis of congenital adrenal hyperplasia, as there is a close linkage between the HLA-B locus and a deficiency in 21-hydroxylase. Furthermore prenatal HLA-determination is of interest in relation to transplantation immunology.

Keywords

Amniotic Fluid Prenatal Diagnosis Congenital Adrenal Hyperplasia Trophoblast Cell Chorionic Villus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Hansen H.E. & L.O. Vejerslev: Hydatidiform Mole and HLA. Methods for HLA-A,B,C-determination. J.Immunol.Method.Google Scholar
  2. Vejerslev L.O., N. Tommerup & A. Hallberg. Hydatidiform moles: Methods for culture and cytogenetic analyses. Cancer Genet. Cytogenet.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • Lars O. Vejerslev
    • 1
    • 2
    • 3
    • 4
  • Hanna E. Hansen
    • 1
    • 2
    • 3
    • 4
  • Jes G. Westergaard
    • 1
    • 2
    • 3
    • 4
  • Finn Søndergaard
    • 1
    • 2
    • 3
    • 4
  1. 1.Department of Medical GeneticsThe J.F.Kennedy InstituteGlostrup, CopenhagenDenmark
  2. 2.University Institute of Forensic GeneticsCopenhagenDenmark
  3. 3.Department of Obstetrics and GynecologyOdense University HospitalOdenseDenmark
  4. 4.Department of Obstetrics and GynecologyCopenhagen Municipal Hospital in HvidovreCopenhagenDenmark

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