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11th Congress of the Society for Forensic Haemogenetics (Gesellschaft für forensische Blutgruppenkunde e.V.) pp 261–267Cite as

Gene Frequency Distribution of F13A and F13B in U.S. Whites, Blacks, Amerindians and Mexican-Americans

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Part of the book series: Advances in Forensic Haemogenetics ((HAEMOGENETICS,volume 1))

Abstract

Coagulation factor XIII (fibrin stabilizing factor) is the precursor of fibrinoligase and calalyses the cross-linking of fibrin mononers into fibrin polymers. FXIII in plasma consists of two subunits, A and B, with the enzymatic activity residing in the A subunit. The B subunit is thought to act as a carrier and regulator of the A subunit. Genetic polymorphisms of the A and B subunits have been described. Reports on the distribution of these polymorphisms have primarily been restricted to Caucasian and Asian populations.(1–13). For this study we phenotyped local White, Black, Mexican American and Amerindian populations using a technique of isoelectric focusing (IEF) and immunoblotting.

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Author information

Authors and Affiliations

  1. Memorial Blood Center of Minneapolis, Minneapolis, Minnesota, 55404, USA

    Dale D. Dykes, Shirley Miller & Herbert Polesky

Authors
  1. Dale D. Dykes
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  2. Shirley Miller
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  3. Herbert Polesky
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Editor information

Editors and Affiliations

  1. von Esmarch-Straße 86, 4400, Münster, Germany

    B. Brinkmann

  2. Frederik V’s Vej 2, 2100, Copenhagen, Denmark

    Klavs Henningsen

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© 1986 Springer-Verlag Berlin Heidelberg

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Dykes, D.D., Miller, S., Polesky, H. (1986). Gene Frequency Distribution of F13A and F13B in U.S. Whites, Blacks, Amerindians and Mexican-Americans. In: Brinkmann, B., Henningsen, K. (eds) 11th Congress of the Society for Forensic Haemogenetics (Gesellschaft für forensische Blutgruppenkunde e.V.). Advances in Forensic Haemogenetics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71150-3_56

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  • DOI: https://doi.org/10.1007/978-3-642-71150-3_56

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16500-2

  • Online ISBN: 978-3-642-71150-3

  • eBook Packages: Springer Book Archive

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