Polymorphisms in Leucocytes: Population Data on Malic Enzyme and Alpha-L-Fucosidase

  • G. A. Siebert
  • K. Rother
Conference paper
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 1)


The genetically determined polymorphisms of mitochondrial Malic Enzyme (E.C. and Alpha-L-Fucosidase (E.C. have been first described in 1972 (Cohen et al.) and in 1974 (Turner et al.), respectevely. Data on population genetics are still scarce, however. The two enzyme systems are readily detectable in human white blood cells and can be demonstrated by routine methods such as starch gel electrophoresis (Malic Enzyme) or Isoelectric Focusing (Fucosidase). In this paper population data obtained from blood donors in southern Germany are presented.


Blood Donor Population Genetic Gene Frequency Population Data Forensic Medicine 
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  1. Cohen, P. T. W., Omenn, G. S.: Human malic enzyme: High frequency polymorphism of the mitochondrial form. Biochem. Genet. 7; 303 (1972).PubMedCrossRefGoogle Scholar
  2. Kömpf, J., and Ritter, H.: Formalgenetik der Polymorphismen Peptidase A, Mitochondriales Malic Enzyme, Alpha Fucosidase, und Gerinnungsfaktor XIII A. Ref. Bd., 10. Int. Tgg. Ges. forens. Blutgruppenkd., München 1983.Google Scholar
  3. Kühnl, P., and Spielmann, W.: Alpha-L-Fucosidase: Darstellung mittels isoelektrischer Fokussierung und Allelfrequenzen in Hessen. Ref. Bd. Ges. forens. Blutgruppenkd., Hamburg 1977.Google Scholar
  4. Siebert, G., Ritter, H., and Kömpf, J.: Mitochondrial Malic Enzyme (E.C. in human leucocytes: Formal genetics and population genetics. Hum. Genet. 51, 319 (1979).PubMedCrossRefGoogle Scholar
  5. Turner, B. M., Beratis, N. G., Turner, V. S., and Hirschhorn, K.: Isizymes of Alpha-L-Fucosidase detectable by starch gel electrophoresis. Clin. Chim. Acta 57, 29 (1974).PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • G. A. Siebert
    • 1
  • K. Rother
  1. 1.Institut für Immunologie und Serologie der UniversitätHeidelbergGermany

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