Abstract
With about 20 HLA-A alleles, 40 B alleles and 10 C alleles, the total number of different HLA-A,B,C haplotypes amounts to 20 × 40 × 10= 8000. This implies that the greater part of the three-locus haplotypes will have low or even very low frequencies and that, even in rather large population samples, the estimates of these frequencies will have relatively considerable standard errors.
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© 1986 Springer-Verlag Berlin Heidelberg
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Nijenhuis, L.E. (1986). Estimation of HLA haplotype frequencies in national or regional populations. In: Brinkmann, B., Henningsen, K. (eds) 11th Congress of the Society for Forensic Haemogenetics (Gesellschaft für forensische Blutgruppenkunde e.V.). Advances in Forensic Haemogenetics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71150-3_44
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DOI: https://doi.org/10.1007/978-3-642-71150-3_44
Publisher Name: Springer, Berlin, Heidelberg
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