Abstract
The Mendelian inheritance of polymorphic DNA sequences makes them useful for paternity determinations. We examined the DNA polymorphisms associated with the genetic loci D14S1 and HRAS1 in more than 100 paternity cases. The objective of these tests was to first determine the phenotypes (ie. the size of polymorphic fragments) of the mother, child and alleged father and second to use this information in assignment of paternity. In addition, the HLA haplotype of these individuals was established and used to determine paternity. A comparison of these two methods for the analysis of paternity cases indicated: 1) the two DNA polymorphisms used in this study excluded the same number of alleged fathers from paternity cases as HLA, 2) both methods resulted in similar paternity indices.
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© 1986 Springer-Verlag Berlin Heidelberg
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Balazs, I. et al. (1986). Application of DNA Polymorphisms to the Determination of Paternity. In: Brinkmann, B., Henningsen, K. (eds) 11th Congress of the Society for Forensic Haemogenetics (Gesellschaft für forensische Blutgruppenkunde e.V.). Advances in Forensic Haemogenetics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71150-3_42
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DOI: https://doi.org/10.1007/978-3-642-71150-3_42
Publisher Name: Springer, Berlin, Heidelberg
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