Alpha-l-Antitrypsine (Pi) Polymorphism. Improved Pi-M-Subtyping by PAGIF with Immobilized Gradients.

  • F. Ferstl
  • H. H. Hoppe
Conference paper
Part of the Advances in Forensic Haemogenetics book series (HAEMOGENETICS, volume 1)

Abstract

The demonstration of the genetically determined alpha-l-antitrypsine (PI) phenotypes may be achieved generally by isoelectrofocusing (IEF) on polyacrylamide gels (PAGIF) with carrier ampholytes. This method which originally was applied at a pH-gradient pH 3.5 — pH 6.does not produce a sufficient resolution quality though recently carrier ampholytes with a pH gradient pH 4.2 – 4.9 are offering an improved resolution (3).

Keywords

Polyacrylamide Aqua 

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Lit.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • F. Ferstl
    • 1
  • H. H. Hoppe
    • 1
  1. 1.Zentralinstitut für TransfusionsmedizinHamburg Filbektal 111Germany

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