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The Preparation of Colloidal Gold Probes and Their Use as Marker in Electron Microscopy

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Book cover Advanced Techniques in Biological Electron Microscopy III

Abstract

Cytochemical marking comprizes the visualization and localization of target molecules (targets) in cells and tissues. The targets are recognized by identifiers such as: antibodies (for antigens), lectins (for polysaccharides and glycoproteins), enzymes (for their substrate, e.g., polynucleotides, collagen, elastin, etc...), ligands (for their receptor or binding site), and derivatized polynucleotides (for in situ hybridization on isolated chromosomes and tissue sections).

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De Mey, J., Moeremans, M. (1986). The Preparation of Colloidal Gold Probes and Their Use as Marker in Electron Microscopy. In: Koehler, J.K. (eds) Advanced Techniques in Biological Electron Microscopy III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71135-0_6

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