Cytological Diagnosis of Pancreatic Tumors

  • G. Mikuz
Conference paper


Until the early 1970s, pre- and intraoperative histological diagnosis of pancreatic tumors was performed by means of wedge biopsies or the Vim-Silvermann needle [1, 5]. Since, however, even in pancreas resection specimens it was often extremely difficult to distinguish between highly differentiated ductal carcinomas and ductal hyperplasias, none of these methods gave the desired accuracy. The ensuing complications were also high (l%–20%); some authors even calculated a 9% mortality rate [4]. Shortly after the first promising reports appeared on the intra-operative cytological dignosis of pancreatic lesions by means of fine-needle biopsies, this method was introduced at the authors’ clinic [3, 6]. Since then, various methods have been presented that enable pancreatic tumors to be localized before surgery [2], thereby making them accessible for fine-needle biopsies (FNBs). Of all these methods, ultrasound-guided puncture is certainly the simplest and the most comfortable for the patient.


Pancreatic Tumor Pancreatic Lesion Islet Cell Tumor Cytological Diagnosis Ampullary Carcinoma 
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  1. 1.
    Klöppel G, Heitz PU (1984) pancreatic pathology. Churchill livingstone, edinburghGoogle Scholar
  2. 2.
    Koss LG, Woyke S, Olszewski W (1984) aspiration biopsy. Igaku-Shoin, New YorkGoogle Scholar
  3. 3.
    Lederer B, Bodner E (1974) Intraoperative Abklärung tumoröser Veränderungen des Pan- kreaskopfes mittels der Feinnadelsaugbiopsie. Dtsch Med Wochenschr 99: 993–996CrossRefGoogle Scholar
  4. 4.
    Lightwood R, Reber HA, Way LW (1976) The Risk And Accuracy Of Pancreatic Biopsy. AM J SURG 132: 189–194PubMedCrossRefGoogle Scholar
  5. 5.
    McLoughlin MJ, Ho CS, Langer B, Mc Hattie J, Tao LC (1978) Fine Needle Aspiration Biopsy Of Malignant Lesions In And Around The Pancreas. Cancer 41: 2413–2419PubMedCrossRefGoogle Scholar
  6. 6.
    Mikuz G, Lederer B, Bodner E (1978) 6-jährige erfahrung mit der intraoperativen abklärung tumoröser veränderungen des pankreaskopfes mittels der feinnadelsaugbiopsie. Verh Dtsch Ges Pathol 62: 379Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • G. Mikuz
    • 1
  1. 1.Institute of PathologyUniversity of InnsbruckInnsbruckAustria

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