Neural Transmitters and Central Mechanisms in Primary Hypertension

  • P. I. Korner
  • E. Badoer
  • G. A. Head
Conference paper


Much of our current knowledge about the operation of the autonomic nervous system is based on input-output analysis of the mechanisms through which particular disturbances evoke distinctive autonomic response patterns. Most of this work has been based on analysing the responses to stimuli of relatively short duration, of only minutes and hours. However, our focus on circulatory regulation shifts to a longer time frame when considering the pathogenesis of hypertension, or the mechanisms of action of centrally acting antihypertensive drugs. Some of the latter are particularly valuable for probing molecular mechanisms, such as the neurotransmitters and membrane receptors, of cardiovascular neurons.


Mean Arterial Pressure Transmitter Release Primary Hypertension Ventrolateral Medulla Conscious Rabbit 
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Copyright information

© Springer-Verlag Berlin Heildelberg 1986

Authors and Affiliations

  • P. I. Korner
    • 1
  • E. Badoer
    • 1
  • G. A. Head
    • 1
  1. 1.Baker Medical Research InstitutePrahranAustralia

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