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Heat Capacities of Biological Macromolecules

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Thermodynamic Data for Biochemistry and Biotechnology

Abstract

Thermal measurements of biological objects are gaining increasing importance in molecular-biological studies (see, e.g., reviews [1–9]. This is due both to recent developments in the field of thermophysical instruments (including scanning differential microcalorimeters [10–18], and to advances in configurational statistics and statistical mechanics of macromolecules, the statistical-thermodynamic theory of phase transitions in biopolymers, and the theory of solutions of macromolecules.

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Abbreviations

c:

heat capacityheat capacityheat capacityheat capacity

c*(T):

variation of heat capacity with temperature determined by measuring finite temperature changes caused by [mite amounts of thermal energy at different temperatures. c*(T) is in the limit of LlT ....Oequal to c(n.

cp :

isobaric specific heat capacity [J g-1 K-1]

Cp,1 :

isobaric partial specific heat capacity of solvent

Cp,2 :

isobaric partial specific heat capacity of solute

cp,s :

heat capacity in solid state

δCp,s :

average difference between speciffic heat capacities ofvarious proteins in the solid state

∆cp :

average difference between the specific heat capacities of the unfolded and native state for a given protein

∆cp(ion):

heat capacity contribution resulting from ionization

\(\rm \frac{{ - (G^0- H^0 )}}{T} = \int\limits_0^T {\frac{{C^p }}{T}dt - \frac{1}{T}\int\limits_0^T {C_p dt} } \) :

Gibbs energy function

G0 :

standard Gibbs energy

H 00 :

standard enthalpy at 0K It is not specified here, whether G and Hg represent molar or specific quantities or refer to another amount ofmaterial (such as 100 g). These definitions are made in the tables. A conversion factor of 1 cal=4.186 J has been used throughout this chapter.

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Authors
  1. George M. Mrevlishvili
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Editors and Affiliations

  1. Institut für Biophysik und Physikalische Biochemie, Universität Regensburg, Universitätsstraße 31, 8400, Regensburg, Germany

    Hans-Jürgen Hinz

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Mrevlishvili, G.M. (1986). Heat Capacities of Biological Macromolecules. In: Hinz, HJ. (eds) Thermodynamic Data for Biochemistry and Biotechnology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71114-5_5

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  • DOI: https://doi.org/10.1007/978-3-642-71114-5_5

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