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Mechanisms of Differential Nerve Block

  • S. A. Raymond
  • A. J. Gissen
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 81)

Abstract

Local anesthesia has been in active clinical use for 100 years. During the past 50 years surprisingly little change has occurred in drugs or techniques. Recently there has been a rapid increase in the demands placed on the anesthesiologist: The parturient needs pain relief but does not wish to prolong her labor by decrease in motor function. The patient with chronic pain needs relief but a clear sensor-ium so he may continue as an active member of society. Patients suffering from various neurological disorders with uncontrollable muscle spasms need relief without loss of sensation. These demands can be satisfied only partially with available methods of local anesthesia.

Keywords

Peripheral Nerve Conduction Velocity Myelinated Fiber Conduction Block Compound Action Potential 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • S. A. Raymond
  • A. J. Gissen

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