CT Absorption Analysis in Intracranial Tumor Diagnostics

  • W. Hopfenmüller
Conference paper
Part of the Advances in Neurosurgery book series (NEURO, volume 14)


At the beginning of the 1970s a new era began in the diagnosis of compressive processes with the development of computerized tomography by G.N. Hounsfield (5). This diagnostic aid made direct topographical findings possible for the first time, and, within particular limits, differential diagnoses could be achieved which approached the possibilities of macroscopic pathology. Although approaches to absorption analysis have indeed been found, even in textbooks (6) the images provided by computerized tomography are presently assessed only by visual means. In connection with this, it should be borne in mind that the human eye is capable of differentiating only about 10 gray and 15 color shades. For this reason, an attempt was made by an interdisciplinary working group (consisting of neurosurgeons, neuropathologists, bio-mathematicians, and computer scientists) to analyze the actual information medium of the CT image: the absorption, or density, values of the pictures obtained. Primary interest was initially directed to intracranial pathological processes and to the search for characteristic absorption value distribution in meningiomas (n = 40), glioblastomas (n = 30), and cerebral abscesses (n = 36) in unmodified images and in those featuring contrast enhancement.


Brain Abscess Absorption Analysis Color Shade Cerebral Abscess Contrast Agent Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Fury, B., Riedwyl, H.: Angewandte multivariate Statistik. Fischer, Stuttgart New York 1983Google Scholar
  2. 2.
    Hopfenmüller, W., Augustin, D., Meese, W.: EDV-Programme zur Verarbeitung von Computertomogrammen. EDV in Medizin und Biologie 11(1), 28–30 (1980)Google Scholar
  3. 3.
    Hopfenmüller, W., Augustin, D., Meese, W.: Computerprogramme für die Absorptionsanalysen in der kranialen Computertomographie. EDV in Medizin und Biologie 15(1), 4–7 (1984)Google Scholar
  4. 4.
    Hopfenmüller, W., Augustin, D., Meese, W.: Bildgebende Verfahren bei CT-Absorptionsanalysen intrakranieller pathologischer Prozesse. EDV in Medizin und Biologie 15(3/4), 65–73 (1984)Google Scholar
  5. 5.
    Hounsfield, G.H.: Computerized transverse axial scanning (tomography): Part 1. Description of system. Br. J. Radiol. 46, 1016–1022 (1973)PubMedCrossRefGoogle Scholar
  6. 6.
    Kazner, E., Wende, S., Grumme, Th., Lanksch, W., Stochdorph, O.: Computertomographie intrakranieller Tumoren aus klinischer Sicht. Springer, Berlin Heidelberg New York 1981Google Scholar
  7. 7.
    Lachenbruch, P.A.: Discriminant analysis. Biometrics 35, 69–85 (1979)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • W. Hopfenmüller
    • 1
  1. 1.Institut für Medizinische Statistik und DokumentationFreie Universität BerlinBerlin 45Germany

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