Intracarotid Amobarbital Testing and Assessment of Speech Laterality

  • H. Silfvenius
Conference paper


Intracarotid injection of sodium amobarbital (Amytal) transiently blocks the perfused cerebral hemi-sphere. It allows for investigations of various intra- and interhemispheric functions which must be clarified in the individual patient and which are of importance for the understanding of brain function in neurological disease. The bilateral intracarotid amobarbital test which Wada and Rasmussen (1960) used preoperatively on patients with intractable epilepsy has given otherwise unobtainable information on lateralization of speech and memory functions (Milner et al. 1962,1964). The test may be used when there is uncertainty about speech lateralization and memory function, side of epileptic lesion, EEG, or neuropsychological findings.


Epileptic Patient Frontal Lesion Speech Laterality Intracarotid Injection Nondominant Hemisphere 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • H. Silfvenius
    • 1
  1. 1.Department of NeurosurgeryUniversity HospitalUmeåSweden

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