Particular Problems of Histological Preparation and Assessment: Advanced Methods

  • Erhard Meyer-Breiting
  • Arne Burkhardt


The histological preparation of whole larynges in the form of multiple serial sections is made considerably more difficult by the difference in hardness of the various tissue types in this organ, and in particular by the age-dependent ossification of cartilaginous parts of the skeleton. The detailed knowledge regarding the spread of endolaryngeal tumours that is of invaluable worth for diagnosis and therapy can be most readily gained from whole-organ sections, in which the behaviour of the tumours in relation to the different anatomical structures in the larynx is evident and more exactly discernible.


Precancerous Lesion Advance Method Premalignant Lesion Laryngeal Carcinoma Nuclear Area 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Erhard Meyer-Breiting
    • 1
  • Arne Burkhardt
    • 2
  1. 1.Zentrum der HNO-HeilkundeUniversitätsklinikum FrankfurtFrankfurt am Main 70Germany
  2. 2.Pathologisches Institutder Universität BernBernGermany

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