The Ontogeny of the Immune Response: The Role of Maternal Factors
The newborn infant must be capable of coping with the many microorganisms to which it is exposed after birth. Most of the contact between the neonate and the microorganisms occurs on mucous membranes, which represent extensive surfaces of thin lining protecting the integrity of the host. For the understanding of the host-parasite relationship in the young infant and the ontogeny of immunity, we need to determine what factors microorganisms might use to colonize and possibly invade the mucosal membranes.
KeywordsAlbumin Carbohydrate Peri Stein Oligosaccharide
Unable to display preview. Download preview PDF.
- Brambell FWR (1971) The transmission of passive immunity from mother to young. North-Holland, Amsterdam.Google Scholar
- Carlsson B, Ahlstedt S, Hanson LÅ, Lidin-Janson B, Lindblad BS, Sultana R (1976) Escherichia coli O antibody content in milk from healthy Swedish mothers and mothers from a very low socioeconomic group of a developing country. Acta Paediatr Scand 65: 413–417.Google Scholar
- Dahlgren UIH, Wold AES, Ahlstedt S, Hanson LÅ (1986) Tolerization of rat pups to ovalbumin in mother’s diet, (to be published)Google Scholar
- Hanson LÅ, Carlsson B, Dahlgren U, Mellander L, Svanborg Eden C (1980) The secretory IgA system in the neonatal period. In: Perinatal infections. Excerpta Medica/Elsevier/North-Holland, Amsterdam, pp 187–204 (Ciba Foundation symposium no. 77)Google Scholar
- Hanson LÅ, Söderström T, Brinton C, Carlsson B, Larsson P, Mellander L, Svanborg Edén C (1983) Neonatal colonization with Escherichia coli and the ontogeny of the antibody response. Progr Allergy 33: 40–52.Google Scholar
- Hanson LÅ, Brandtzaeg P (1986) Mucosal defense. In: Stiehm ER (ed) Immunologic disorders in infants and children, 3rd edn. Saunders Philadelphia (in press)Google Scholar
- Hanson LÅ, Jalil F, Khan SR, Hasan R, Karlberg J, Mellander L, Carlsson B, Adlerberth I, Söderström T, Kaleen A, Lindblad BS (1986) Breast feeding in reality. In: Maternal-environmental factors in human lactation. Oaxaca, Mexico (in press)Google Scholar
- Mellander L, Carlsson B, Hanson LÅ (1986) Secretory IgA and IgM antibodies to E.coli and poliovirus type I antigens occur in amniotic fluid, meconium and saliva from newborns. Clin Exp Immunol (in press)Google Scholar
- Söderström T, Stein K, Brinton JR CC, Hosea S, Burch C, Hansson HA, Karpas A, Schneerson R, Sutton A, Vann WF, Hanson LÅ (1983) Serological and functional properties of monoclonal antibodies to Escherichia coli type 1 pilus and capsular antigens. Progr Allergy 33: 259–274.Google Scholar