Dosage of Serum Acetylcholine Receptor Antibodies

  • Bernard W. Fulpius


Anti-acetylcholine receptor antibodies are usually polyclonal antibodies which are directed against the nicotinic acetylcholine receptor (nAChR) glycoprotein. This definition does not mean that these antibodies necessarily interact with functional parts of the receptor molecule. Anti-nAChR antibodies belong to the G or M class of immunoglobulins, and to any one of their subclasses. Thus, these antibodies represent a rather heterogeneous population of molecules with possibly very different properties if one considers their molecular size, ability to cross the foetoplacental barrier, half-life, resistance to proteolysis, tendency to aggregate and form complexes, capacity to bind complement factors and affinity for the receptor molecule.


Acetylcholine Receptor Receptor Molecule Myoid Cell Myasthenic Patient Thymic Extract 
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© Springer-Verlag Berlin Heidelberg 1990

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  • Bernard W. Fulpius

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