Zusammenfassung
Die Aufnahme eines Peptidhormons in die Zelle ist ein spezifischer Vorgang, der an die Präsenz des entsprechenden Rezeptors an der Zelloberfläche gebunden ist. Nach Erkennung und Komplexbildung werden die Hormonrezeptorkomplexe in Gruppen oder Clustern in Form eines endozytotischen Vesikels in die Zelle aufgenommen. Dieser Vorgang dient der Metabolisierung des Hormons, und bei einigen Hormonen, wie z.B. dem Prolaktin, auch der Metabolisierung des Rezeptors [101.
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Blossey, H.C., Gaier, B., Zaltsman, Y., Kohen, F. (1986). Biologische Erkennung eines Prolaktin-Daunomycin-Liganden in vitro und in vivo. In: Nagel, G.A. (eds) Mammakarzinome. Neue Perspektiven experimenteller und klinischer Therapieforschung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71041-4_16
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