Labile Sagittal Sinus Pressures in the Cat
It is an important assumption in most studies on cerebrospinal fluid (csf) dynamics, that the pressure in the venous sinuses (Pss) does not change when the csf pressure (Pc) changes (Davson, Hollingsworth et al. 1970; Sullivan, Miller et al. 1979). By assuming a constant Pss, the changes in csf absorption with changes in Pc can be related to the Pc change alone without reference to the pressure in the recipient vessels, Pss. If however, the Pss changes in the same direction as a change in Pc, then csf outflow resistance will be overestimated if the no-change in Pss assumption is made. If Pss changes in the opposite direction to Pc then outflow resistance will be underestimated.
KeywordsVenous Sinus Bolus Infusion Constant Rate Infusion Outflow Resistance Cerebrospinal Fluid Pressure
Unable to display preview. Download preview PDF.