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Control of Intracranial Pressure in Traumatic Brain Injury. Our Experience with Gammahydroxybutyric Acid or Thiopental, and Fentanyl

  • P. Dabadie
  • P. Maurette
  • J. F. Brule
  • C. Kays
  • J. Destandeau
  • J.-P. Castel
  • P. Erny
Conference paper

Abstract

In cases of severe head injury barbiturates are commonly administered to control increased intracranial pressure (ICP). Despite beneficial influences, in some cases there are also frequent deleterious effects.

Keywords

Traumatic Brain Injury Intracranial Pressure Glasgow Outcome Scale Severe Head Injury Hydroxybutyric Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Escuret E, Baldy-Moulinier M, Roquefeuil B, Frerebeau P (1979) Gamma hydroxybutyrate as a substitute for barbiturate therapy in comatose patients with head injuries. Acta Neurol Scand, Suppl 72: 38–39Google Scholar
  2. Kenning JA, Steven MT, Saunders RO (1981) Upright patient positioning in the management of intracranial hypertension. Surg Neurol 15: 148–152PubMedCrossRefGoogle Scholar
  3. MacMillan V (1978) The effects of gamma-hydroxybutyrate and gamma-butyrolactone upon the energy metabolism of the normoxic and hypoxic rat brain. Brain Res 146: 177–187PubMedCrossRefGoogle Scholar
  4. Moss E, Powell D, Gibson RM, McDowall DG (1978) Effects of fentanyl on intracranial pressure and cerebral perfusion pressure during hypocapnia. Br J Anaesth 50: 779–784PubMedCrossRefGoogle Scholar
  5. Narayan RK, Kishore PRS, Becker DP, Ward JD, Enas GG, Greenberg RP, Da Silva AD, Lipper MH, Choi SC, Mayhalt CG, Lutz III HA, Young HF (1982) Intracranial pressure: to monitor or not to monitor. J Neurosurg 56: 650–659PubMedCrossRefGoogle Scholar
  6. Sault TG, Ducker TB (1982) Effect of intracranial pressure monitoring and aggressive treatment on mortality in severe head injury. J Neurosurg 56: 498–503CrossRefGoogle Scholar
  7. Ward JD, Becker DP, Miller JD, Choi SC, Marmarou A, Wood C, Newlon PG, Keenan R (1985) Failure of prophylactic barbiturate coma in the treatment of severe head injury. J Neurosurg 62: 383–388PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • P. Dabadie
    • 1
  • P. Maurette
    • 1
  • J. F. Brule
    • 1
  • C. Kays
    • 1
  • J. Destandeau
    • 1
  • J.-P. Castel
    • 1
  • P. Erny
    • 1
  1. 1.Service Réanimation ChirurgicaleHôpital PellegrinBordeauxFrance

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