Abstract
It is still controversial whether edema fluid around a malignant brain tumor is derived only from capillaries within the tumor or is also produced outside the tumor. The purpose of this study is to clarify the region of increased capillary permeability, and the spreading of serum proteins and edematous fluid from capillaries, using a double autoradiographic method. The effect of steroids on peritumoral edema was also examined.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bartkowski HM (1984) Peritumoral edema. Prog exp Tumor Res 27: 177–190
Blasberg RG, Fenstermacher JD, Patlak CS (1983) Transport of aaminoisobutyric acid across brain capillary and cellular membranes. J Cereb Blood Flow Metab 3: 8–32
Groothuis DR, Molnar P, Blasberg RG (1984) Regional blood flow and blood-to-tissue transport in five brain tumor models. Prog Exp Tumor Res 27: 132–135
Hossmann K-A, Huter T, Oschlies V (1983) The effect of dexamethasone on serum protein extravasation and edema development in experimental brain tumors of cat. Acta Neuropathol 60: 223–231
Nagashima T, Tamura A, Matsutani M, Orii H, Tsujita Y (1983) Regional cerebral blood flow in experimental brain tumor: Comparative study between blood flow and neuropathological characteristics. J Cereb Blood Flow Metabol 3 (suppl 1): S69–S70
Nagashima T, Matsutani M, Tamura A, Orii H (1985) Regional blood flow of experimental brain tumors with special reference to effects of chemotherapy and radiotherapy. Brain Nerve 37:287 –294
Yamada K, Bremer AM, West CR (1979) Effects of dexamethasone on tumor-induced brain edema and its distribution in the brain of monkeys. J Neurosurg 50: 361–367
Yamada K, Ushio Y, Hayakawa T, Kato A, Yamada N, Mogami H (1982) Quantitative autoradiographic measurements of blood brain barrier permeability in the rat glioma model. J Neurosurg 57: 394–398
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Tamura, A. et al. (1986). Changes of Capillary Permeability in Experimental Brain Tumor. In: Miller, J.D., Teasdale, G.M., Rowan, J.O., Galbraith, S.L., Mendelow, A.D. (eds) Intracranial Pressure VI. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70971-5_105
Download citation
DOI: https://doi.org/10.1007/978-3-642-70971-5_105
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70973-9
Online ISBN: 978-3-642-70971-5
eBook Packages: Springer Book Archive