Causes and Consequences of Raised Intracranial Pressure in Head Injuries
There is still disagreement about the value of monitoring and treating Intracranial Pressure (ICP) in severely head injured patients (Stuart et al. 1983). This reflects continuing uncertainties about what mechanisms are responsible for increased ICP, if these differ in different injuries, and also doubts about the relationship between ICP and brain damage. We review a range of investigations we have performed on severely injured adults in order to study changes in the volumes of the intracranial constituents that may indicate raised ICP after head injury. The results provide a basis for understanding the causes and consequences of traumatic intracranial hypertension.
KeywordsIodide Neurol Xenon Doyle Nitol
Unable to display preview. Download preview PDF.
- Galbraith S, Cardoso E, Patterson J, Marmarou A (1984). The water content of white matter after head injury in man. In: Go KG and Baethmann AF. Recent Progress in the Study and Therapy of Brain Oedema. Plenum Publishing Corporation pp 323–330Google Scholar
- Graham DI, Lawrence AE, Hume Adams J, Doyle D, McLellan D (1986). Brain Damage Secondary to a High Intracranial Pressure in Head Injury. In: ICP VI. Eds. Miller JD, Teasdale G, Rowan JR, Galbraith S, Mendelow AD. Springer-Verlag, Berl in HeidelbergGoogle Scholar
- Mendelow AD, Teasdale G, Teasdale E, Matheson M, Russell T (1983). Cerebral Blood Volume and Intracranial Pressure in Head Injured Patients. In: ICP V. Ed. Ishii S, Nagai H, Brock M. Springer-Verlag. Berlin Heidelberg p495–500Google Scholar
- Mendelow AD, Teasdale GM, Russell T, Flood J, Patterson J, Murray GD (1985). Cerebral Blood Flow and Perfusion Pressure in Human Head Injury. J Neurosurgery (In Press)Google Scholar
- Murphy A, Teasdale E, Matheson M, Galbraith S, Teasdale G (1983). Relationships between CT indices of brain swelling and Intracranial Pressure after head injury. In: ICP V. Ed. Ishii S, Nagai H, Brock M. Springer-Verlag. Berlin Heidelberg p562–566Google Scholar
- Obrist WD, Langfitt TW, Jaggi JC, Cruz J, Gennarelli TA (1984). Cerebral Blood Flow and metabolism in comatose patients with acute head injury: Relationship to intracranial pressure. J Neurosurg 61: 241–253Google Scholar
- Teasdale E, Cardoso E, Galbraith S, Teasdale G (1984). CT Scan in Severe Diffuse Head Injury: Physiological and Clinical Correaltions. J Neurol Neurosurg & Psychiat 47: 600–603Google Scholar