Zusammenfassung
Vorstellungen über die Materie, aus welcher das Gehirn besteht, und welchen Änderungen sie während dessen Funktion unterworfen sein könnte, gab es natürlich schon früh in der Geschichte der Menschheit, und im weitesten Sinne ist das Konzept einer chemischen Ursache von Geisteskrankheiten wohl so alt wie die Geschichte der Medizin. Eine wichtige Voraussetzung jedoch, dieses Konzept systematisch zu analysieren und zu konkretisieren, nämlich eine genauere Kenntnis der chemischen Zusammensetzung des Hirns, wurde erst mit dem Entstehen und der Entwicklung der organischen Chemie und ihren analytischen Techniken geschaffen.
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Literatur
Blaschko H (1972) Catecholamines 1922–1971 (Chap.1). In: Eichler O, Farah A, Herken H, Welch AD (eds) Handb. exp. Pharmakol., Band XXXIII. Berlin, Springer pp 1–15
Beckmann H, Goodwin FK (1975) Antidepressant response to tricyclics and urinary MHPG in unipolar patients: clinical response to imipramine or amitriptyline. Arch gen Psychiat 32: 17–21
Bowers MB (1980) Biochemical processes in schizophrenia: an update. Schizophrenia Bull 6: 393–430
Campbell JD (1953) Manic-depressive disease. Lippincott JB, Philadelphia
Carlsson A, Lindquist M (1963) Effect of chlorpromazine and haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain. Acta Pharmacol Toxicol 20:140–144
Erspamer V (ed) (1965) Handb. exp. Pharmacol. Band XIX. Springer, Berlin
Flor-Henry P (1976) Lateralized temporal-limbic dysfunction und psychopathology. Ann N Y Acad Sci 280: 777–795
Garnett ES, Firnau G, Nahmias C, Lang AE, Ballinger McMaster J (1984) Intracerebral and quantitative measurement of intracerebral dopamine metabolism in health and disease. Clin Neuropharmacol 7 (Suppl.1): 530–531 (S 290)
Garnett ES, Firnau G, Nahmias C (1983) Dopamine visualized in the basal ganglia of living man. Nature 305: 137–138
Garnett S, Firnau G, Nahmias C, Chirakal R (1983) Striatal dopamine metabolism in living monkeys examined by positron emission tomography. Brain Res: 280: 169–171
Hoffer A, Osmond H (1960) The chemical basis of clinical psychiatry. Thomas ChC, Springfield 111
Horrobin DF (1977) Schizophrenia as a prostaglandin deficiency disease. Lancet I: 936–937
Kelwala S, Jones D, Sitaram N (1983) Monoamine metabolites as predictors of antidepressant response: a critique. Prog Neuro Psychopharmacol & Biol Psychiat 7: 229–240
Kety SS (1975) Biochemistry of the major psychoses (Chap.2.7). In: Freedman AM, Kaplan HI, Sadock BJ (eds) Comprehensive textbook of psychiatry. Williams & Wilkins, Baltimore pp 178–187
Lapin IP, Oxenkrug GF (1969) Intensification of the central serotonergic processes as a possible determinant of the thymoleptic effort. Lancet I: 132–136
Lajtha A (ed) (1970) Handb. of Neurochemistry. Plenum Press, New York
Mackay AV (1984) High dopamine in the left amygdala. Trends in Neurosci 7: 107–108
McIlwain H (1958) Chemical contributions, especially from the nineteenth century, to knowledge of the brain and its functioning. In: Poynter FN (ed) The brain and its functions. Blackwell Scientific Publications, Oxford, pp 167–186
Muscettola G, Potter WZ, Pickar D, Goodwin, FK (1984) Urinary 3-methoxy-4-hydroxyphenylglycol and major affective disorders. Arch gen Psychiat 41: 337–342
Pauling L (1968) Orthomolecular psychiatry. Science 160: 265 – 271
Phelps ME (1984) Principles of biochemical assays with positron CT. Clin Neuropharmacol 7 (Suppl 1): 520–521 (S285)
Post RM, Uhde TW, Ballenger JC, Bunney WE (1982) Carbamazepine, temporal lobe epilepsy, and manic-depressive illness. In: Koella WP, Trimble MR (eds) Temporal lobe epilepsy, mania, and schizophrenia and the limbic system. Karger, Basel, pp 117–156
Ragheb M, Ban TA (1982) Prostaglandins and schizophrenia: a review. Prog Neuro Psychopharmacol Biol Psychiat 6: 87–93
Reynolds GP (1983) Increased concentrations and lateral asymmetry of amygdala dopamine in schizophrenia. Nature 305: 527–529
Rodnight R (1983) Schizophrenia: some current approaches. J Neurochem 41: 12–21
Schildkraut JJ (1965) The catecholamine hypothesis of affective disorders: A review of supporting evidence. Amer J Psychiat 122: 509–522
Siever LJ, Uhde TW, Jimerson DC, Kafka MS, Lake CR, Targum S, Murphy DL (1983) Clinical studies of monoamine receptors in the affective disorders and receptor changes with antidepressant treatment. Prog Neuro Psychopharmacol Biol Psychiat 7:249–261
Smythies JR (1984) The transmethylation hypotheses of schizophrenia reevaluated. Trends in Neurosci 7:45–47
Stevens JR, Livermore A (1978) Kindling of the mesolimbic dopamine system: animal model of psychosis. Neurology 28: 36–46
Swann AC, Maas JW, Hattox SE, Landis H (1980) Catecholamine metabolites in human plasma as indices of brain function: effects of debrisoquin. Life Sci 27: 1857–1862
Wagner HN, Burns HD, Dannais RF, et al. (1983) Imaging dopamine receptors in the human brain by positron tomography. Science 221: 1264–1266
Wagner HN, Wong DF, Dannals RF, et al. (1984) Effect of age on dopamine receptors in the human brain. Clin Neuropharmacol 7 (Suppl 1): 540–541
Wagner HN, Wong DF, Dannals RF, et al. (1984) Effect of age on dopamine receptors in the human brain. Clin Neuropharmacol 7 (Suppl 1): (S 296)
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Waldmeier, P.C. (1986). Der Beitrag der Biochemie zur Psychiatrischen Forschung und Therapie. In: Heimann, H., Gaertner, H.J. (eds) Das Verhältnis der Psychiatrie zu ihren Nachbardisziplinen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70952-4_6
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DOI: https://doi.org/10.1007/978-3-642-70952-4_6
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