History. Dalrymple first described the plasma cell myeloma in 1848, and in the same year Bence Jones discovered the urinary protein that was named after him (quoted in Dominok and Knoch 1977). The term “multiple myeloma” was introduced in 1873 (von Rustitzky). In 1889 Kahler published a complete description of the disease. It was not until 1920 that the lesion was recognized as being a plasma cell tumor (Wallgren). The term plasmacytoma was introduced in 1940 (Apitz).
SynonymsKahler’s disease multiple myeloma solitary myeloma myelomatosis plasma cell myeloma malignant plasmoma.
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